Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …

Curcumin derived from the tropical plant Curcuma longa has a long history of use as a
dietary agent, food preservative, and in traditional Asian medicine. It has been used for …

Exposure of tumor cells to clinically relevant doses of ionizing radiation causes DNA
damage as well as mitochondria-dependent generation of reactive oxygen species. DNA …

The range of radiation threats we face today includes everything from individual radiation
exposures to mass casualties resulting from a terrorist incident, and many of these exposure …

Presenilins (PS, PS1/PS2) are necessary for the proteolytic activity of γ-secretase, which
cleaves multiple type I transmembrane proteins including Alzheimer's β-amyloid precursor …

The acute radiation syndrome (ARS) is defined as the signs and symptoms that occur within
several months after exposure to ionizing radiation (IR). This syndrome develops after total …

In an attempt to further elucidate the pathomechanisms in oral squamous cell carcinoma
(OSCC), gene expression profiling was performed using a whole-transcriptome chip that …

Head and neck cancers (HNC) are a biologically diverse set of cancers that are responsible
for over 660,000 new diagnoses each year. Current therapies for HNC require a …

Cortactin is an actin-binding Src substrate involved in cell motility and invasion. In this study,
we sought to examine the prognostic importance of cortactin protein expression in head and …