Effects of mesenchymal stem cell‐derived paracrine signals and their delivery strategies
Mesenchymal stem cells (MSCs) have been widely studied as a versatile cell source for
tissue regeneration and remodeling due to their potent bioactivity, which includes …
tissue regeneration and remodeling due to their potent bioactivity, which includes …
Homing of endogenous stem/progenitor cells for in situ tissue regeneration: promises, strategies, and translational perspectives
FM Chen, LA Wu, M Zhang, R Zhang, HH Sun - Biomaterials, 2011 - Elsevier
Stem cell-based therapy has been one of the best documented approaches in regenerative
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …
Extracellular vesicles released from mesenchymal stromal cells modulate miRNA in renal tubular cells and inhibit ATP depletion injury
RS Lindoso, F Collino, S Bruno, DS Araujo… - Stem cells and …, 2014 - liebertpub.com
The mechanisms involved in renal repair by mesenchymal stromal cells (MSCs) are not
entirely elucidated. The paracrine secretion of bioactive molecules has been implicated in …
entirely elucidated. The paracrine secretion of bioactive molecules has been implicated in …
Surface marker expression in small and medium/large mesenchymal stromal cell-derived extracellular vesicles in naive or apoptotic condition using orthogonal …
R Skovronova, C Grange, V Dimuccio, MC Deregibus… - Cells, 2021 - mdpi.com
Extracellular vesicles released by mesenchymal stromal cells (MSC-EVs) are a promising
resource for regenerative medicine. Small MSC-EVs represent the active EV fraction. A bulk …
resource for regenerative medicine. Small MSC-EVs represent the active EV fraction. A bulk …
Transplantation of bone marrow-derived MSCs improves cisplatinum-induced renal injury through paracrine mechanisms
Mesenchymal stem cells (MSCs) have been reported to preserve renal function in various
models of acute kidney injury (AKI). Different routes were used to transplant MSCs but the …
models of acute kidney injury (AKI). Different routes were used to transplant MSCs but the …
[HTML][HTML] MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice
SR Mulay, D Thomasova, M Ryu, HJ Anders - Kidney international, 2012 - Elsevier
Murine double minute (MDM)-2, an E3 ubiquitin ligase, promotes cancer cell survival and
growth, by degrading the cell cycle regulator p53. Antagonism of MDM2 by the small …
growth, by degrading the cell cycle regulator p53. Antagonism of MDM2 by the small …
Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemia-reperfusion in cyclosporine-immunosuppressed rats
C Alfarano, C Roubeix, R Chaaya… - Cell …, 2012 - journals.sagepub.com
Ischemia-reperfusion and immunosuppressive therapy are a major cause of progressive
renal failure after kidney transplantation. Recent studies have shown that administration of …
renal failure after kidney transplantation. Recent studies have shown that administration of …
The role of mesenchymal stem cells in chemotherapy-induced gonadotoxicity
Background The therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-
MSCs) against cisplatin-induced nephrotoxicity has been reported, however, its efficacy in …
MSCs) against cisplatin-induced nephrotoxicity has been reported, however, its efficacy in …
[HTML][HTML] Migration of bone marrow–derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study
Background context Mobilization and homing of bone marrow–derived cells (BMCs) play a
pivotal role in healing and regeneration of various tissues. However, the cellular response of …
pivotal role in healing and regeneration of various tissues. However, the cellular response of …
[HTML][HTML] Current advances of stem cell-based therapy for kidney diseases
CY Wong - World journal of stem cells, 2021 - ncbi.nlm.nih.gov
Kidney diseases are a prevalent health problem around the world. Multidrug therapy used in
the current routine treatment for kidney diseases can only delay disease progression. None …
the current routine treatment for kidney diseases can only delay disease progression. None …