Biomedical application of decellularized scaffolds

F Zhang, H Gao, X Jiang, F Yang, J Zhang… - ACS Applied Bio …, 2023 - ACS Publications
Tissue loss and end-stage organ failure are serious health problems across the world.
Natural and synthetic polymer scaffold material based artificial organs play an important role …

Bioengineering strategies for nephrologists: kidney was not built in a day

AJ Peired, B Mazzinghi, L De Chiara… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: The number of patients with end-stage kidney disease is increasing worldwide,
creating an unprecedented organ shortage. The kidney is a highly complex structure …

Decellularized liver as a translucent ex vivo model for vascular embolization evaluation

Y Gao, Z Li, Y Hong, T Li, X Hu, L Sun, Z Chen, Z Chen… - Biomaterials, 2020 - Elsevier
Transarterial chemoembolization (TACE) is the preferred treatment for patients with
unresectable intermediate stage hepatocellular carcinoma, however currently the …

Renal tissue engineering for regenerative medicine using polymers and hydrogels

SMDS Mohamed, GI Welsh, I Roy - Biomaterials Science, 2023 - pubs.rsc.org
Chronic Kidney Disease (CKD) is a growing worldwide problem, leading to end-stage renal
disease (ESRD). Current treatments for ESRD include haemodialysis and kidney …

[HTML][HTML] Effect of Co-culture of mesenchymal stem cell and glomerulus endothelial cell to promote endothelialization under optimized perfusion flow rate in whole renal …

M Choi, YB Yang, S Park, S Rahaman, G Tripathi… - Materials Today Bio, 2022 - Elsevier
In recent era, many researches on implantable bio-artificial organs has been increased
owing to large gap between donors and receivers. Comprehensive organ based researches …

Decellularized extracellular matrix: the role of this complex biomaterial in regeneration

AGP de Paula, JD de Lima, TSB Bastos… - ACS …, 2023 - ACS Publications
Organ transplantation is understood as a technique where an organ from a donor patient is
transferred to a recipient patient. This practice gained strength in the 20th century and …

Recreating Physiological Environments In Vitro: Design Rules for Microfluidic‐Based Vascularized Tissue Constructs

SY Tan, Z Leung, AR Wu - Small, 2020 - Wiley Online Library
Vascularization of engineered tissue constructs remains one of the greatest unmet
challenges to mimicking the native tissue microenvironment in vitro. The main obstacle is …

Vascular reconstruction: A major challenge in developing a functional whole solid organ graft from decellularized organs

KH Hussein, KM Park, L Yu, SH Song, HM Woo… - Acta Biomaterialia, 2020 - Elsevier
Bioengineering a functional organ holds great potential to overcome the current gap
between the organ need and shortage of available organs. Whole organ decellularization …

Flow-induced glycocalyx formation and cell alignment of HUVECs compared to iPSC-derived ECs for tissue engineering applications

M Lindner, A Laporte, L Elomaa… - Frontiers in Cell and …, 2022 - frontiersin.org
The relevance of cellular in vitro models highly depends on their ability to mimic the
physiological environment of the respective tissue or cell niche. Static culture conditions are …

Pushing the boundaries of innovation: the potential of ex vivo organ perfusion from an interdisciplinary point of view

J Iske, A Schroeter, S Knoedler… - Frontiers in …, 2023 - frontiersin.org
Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid
organs with primary application in allogeneic organ transplantation. EVMP has been …