Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory
L Hogarth - Neuropsychopharmacology, 2020 - nature.com
Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …
affective states, a habit driven by strong stimulus− response associations, or a compulsion …
Stress-induced reinstatement of drug seeking: 20 years of progress
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this
clinical scenario has been studied using a rat model of stress-induced reinstatement of drug …
clinical scenario has been studied using a rat model of stress-induced reinstatement of drug …
Compliance with ecological momentary assessment protocols in substance users: A meta‐analysis
Abstract Background and Aims While there are considerable benefits to Ecological
Momentary Assessment (EMA), poor compliance with assessment protocols has been …
Momentary Assessment (EMA), poor compliance with assessment protocols has been …
Ecological momentary assessment in the investigation of craving and substance use in daily life: a systematic review
F Serre, M Fatseas, J Swendsen… - Drug and alcohol …, 2015 - Elsevier
Background Craving is viewed as a major determinant of relapse in persons with substance
addiction, but this association remains poorly understood due to its time-limited nature and …
addiction, but this association remains poorly understood due to its time-limited nature and …
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research
Background and rationale Results from many clinical studies suggest that drug relapse and
craving are often provoked by acute exposure to the self-administered drug or related drugs …
craving are often provoked by acute exposure to the self-administered drug or related drugs …
Individual differences in nucleus accumbens activity to food and sexual images predict weight gain and sexual behavior
KE Demos, TF Heatherton, WM Kelley - Journal of Neuroscience, 2012 - Soc Neuroscience
Failures of self-regulation are common, leading to many of the most vexing problems facing
contemporary society, from overeating and obesity to impulsive sexual behavior and STDs …
contemporary society, from overeating and obesity to impulsive sexual behavior and STDs …
New findings on biological factors predicting addiction relapse vulnerability
R Sinha - Current psychiatry reports, 2011 - Springer
Relapse is a highly prevalent phenomenon in addiction. This paper examines the new
research on identifying biological factors that contribute to addiction relapse risk …
research on identifying biological factors that contribute to addiction relapse risk …
Effect of childhood physical abuse on cortisol stress response
Rationale Abuse and neglect are highly prevalent in children and have enduring
neurobiological effects. Stressful early life environments perturb the hypothalamic–pituitary …
neurobiological effects. Stressful early life environments perturb the hypothalamic–pituitary …
Sex differences in neural responses to stress and drug cues predicts future drug use in individuals with substance use disorder
K Smith, CM Lacadie, V Milivojevic, N Fogelman… - Drug and alcohol …, 2023 - Elsevier
Abstract Background Substance use disorders (SUDs) are chronically recurring illnesses,
where stress and drug cues significantly increase drug craving and risk of drug use …
where stress and drug cues significantly increase drug craving and risk of drug use …
What goes up, can come down: Novel brain stimulation paradigms may attenuate craving and craving-related neural circuitry in substance dependent individuals
Vulnerability to drug related cues is one of the leading causes for continued use and relapse
among substance dependent individuals. Using drugs in the face of cues may be associated …
among substance dependent individuals. Using drugs in the face of cues may be associated …