A widely held dogma in the preclinical addiction field is that females are more vulnerable
than males to drug craving and relapse. Here, we first review clinical studies on sex …

Opioid addiction is associated with excess mortality, morbidities, and other adverse
conditions. Guided by a life-course framework, we review the literature on the long-term …

Through the vivid, true stories of five people who journeyed into and out of addiction, a
renowned neuroscientist explains why the" disease model" of addiction is wrong and …

Introduction This paper describes methamphetamine (MA) use patterns, specifically the
duration of continuing abstinence (“time to relapse”) for periods averaging 5 years post …

Objective This paper presents a systematic review and meta-analysis of available evidence
on remission rates for substance use disorders (SUDs), providing weighted mean estimates …

These Guidelinesreview the use of medicines such as methadone, buprenorphine,
naltrexone and clonidine in combination with psychosocial support in the treatment of …

Importance One of the main aims of research on nonmedical opioid use (NMOU) is to
reduce the frequency of NMOU behaviors through interventions such as universal …

According to the idea that addiction is a chronic relapsing disease, remission is at most a
temporary state. Either addicts never stop using drugs, or if they do stop, remission is short …

Issues. The toxicology of homicide offenders and victims, and homicide as a cause of death
among psychoactive substance users. Approach. Review of the toxicology of homicide, and …

Opioid use disorder (OUD) is a chronic, relapsing condition with severe negative health
consequences. Previous studies have reported that 5-year opioid abstinence is a good …