The renin angiotensin system as a therapeutic target in traumatic brain injury

S Villapol, ZC Janatpour, KO Affram, AJ Symes - Neurotherapeutics, 2023 - Elsevier
Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …

[HTML][HTML] An overview of mild traumatic brain injuries and emerging therapeutic targets

JP Bielanin, SAH Metwally, SS Paruchuri… - Neurochemistry …, 2023 - Elsevier
The majority of traumatic brain injuries (TBIs), approximately 90%, are classified as mild
(mTBIs). Globally, an estimated 4 million injuries occur each year from concussions or …

PNA6, a Lactosyl Analogue of Angiotensin-(1-7), Reverses Pain Induced in Murine Models of Inflammation, Chemotherapy-Induced Peripheral Neuropathy, and …

MI Sulaiman, W Alabsi, L Szabo, M Hay, R Polt… - International Journal of …, 2023 - mdpi.com
Pain is the most significant impairment and debilitating challenge for patients with bone
metastasis. Therefore, the primary objective of current therapy is to mitigate and prevent the …

Weight-drop model as a valuable tool to study potential neurobiological processes underlying behavioral and cognitive changes secondary to mild traumatic brain …

CA Machado, B da Silva Oliveira, TL Dias… - Journal of …, 2023 - Elsevier
The pathophysiology of post-traumatic brain injury (TBI) behavioral and cognitive changes is
not fully understood, especially in its mild presentation. We designed a weight drop TBI …