Chronic pain has a tremendous personal and socioeconomic impact and remains difficult to
treat. Therefore, it is important to provide an update on the current understanding regarding …

Alzheimer's disease (AD) is characterized by progressive memory and neuronal loss
culminating in cognitive impairment that not only affects a person's living ability but also …

Alzheimer's disease and other idiopathic dementias are associated with epigenetic
transformations. These transformations connect the environment and genes to …

Studies suggest that dysfunction of brain-derived neurotrophic factor (BDNF) is a possible
contributor to the pathology and symptoms of Alzheimer's disease (AD). Several studies …

Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …

Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in
longitudinal cohort epidemiological studies, and endocrinologic evidence suggests …

Background Alzheimer's disease (AD) is an intractable neurodegenerative disorder in the
elderly population, currently lacking a cure. Trichostatin A (TSA), a histone deacetylase …

Brain-derived neurotrophic factor (BDNF) is required for the development of the nervous
system, proper cognitive function and memory formation. While aberrant expression of …

Background/Aims: In the present study, we examined whether DNA methylation of the brain-
derived neurotrophic factor (BDNF) promoter is associated with the manifestation and …

There is considerable interest in traumatic brain injury (TBI) induced by repeated
concussions suffered by athletes in sports, military personnel from combat-and non-combat …