Deciphering spreading mechanisms in amyotrophic lateral sclerosis: clinical evidence and potential molecular processes

PF Pradat, E Kabashi, C Desnuelle - Current opinion in neurology, 2015 - journals.lww.com
Although ALS is clinically heterogeneous, a shared characteristic is the focal onset and the
progressive extension to all body regions. Being viewed until now as just summation of the …

Resting‐state functional connectivity in the rat cervical spinal cord at 9.4 T

TL Wu, F Wang, A Mishra, GH Wilson III… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose Numerous studies have adopted resting‐state functional MRI methods to infer
functional connectivity between cortical regions, but very few have translated them to the …

Recent developments and future avenues for human corticospinal neuroimaging

M Kaptan, D Pfyffer, CG Konstantopoulos… - Frontiers in Human …, 2024 - frontiersin.org
Non-invasive neuroimaging serves as a valuable tool for investigating the mechanisms
within the central nervous system (CNS) related to somatosensory and motor processing …

[HTML][HTML] Functional connectivity in the dorsal network of the cervical spinal cord is correlated with diffusion tensor imaging indices in relapsing-remitting multiple …

AJE Combes, KP O'Grady, BP Rogers, KG Schilling… - NeuroImage: Clinical, 2022 - Elsevier
Focal lesions may affect functional connectivity (FC) of the ventral and dorsal networks in the
cervical spinal cord of people with relapsing-remitting multiple sclerosis (RRMS). Resting …

Longitudinal multiparametric MRI of traumatic spinal cord injury in animal models

LM Chen, F Wang, A Mishra, PF Yang… - Magnetic Resonance …, 2023 - Elsevier
Multi-parametric MRI (mpMRI) technology enables non-invasive and quantitative
assessments of the structural, molecular, and functional characteristics of various …

[HTML][HTML] Functional ultrasound imaging of the human spinal cord

KA Agyeman, DJ Lee, J Russin, EI Kreydin, W Choi… - Neuron, 2024 - cell.com
Utilizing the first in-human functional ultrasound imaging (fUSI) of the spinal cord, we
demonstrate the integration of spinal functional responses to electrical stimulation. We …

Tracking trauma-induced structural and functional changes above the level of spinal cord injury

E Huber, A Curt, P Freund - Current opinion in neurology, 2015 - journals.lww.com
The introduction of sensitive neuroimaging biomarkers will be an essential step forward in
the implementation of interventional trials in which proof-of-concept is currently limited to …

A novel implementation of spinal fMRI demonstrates segmental organisation of functionally connected networks in the cervical spinal cord: A test-retest reliability study

OS Kowalczyk, S Medina, D Tsivaka, SB McMahon… - bioRxiv, 2023 - biorxiv.org
Resting fMRI studies have identified intrinsic spinal cord activity, which forms organised
motor (ventral) and sensory (dorsal) resting-state networks. However, to facilitate the use of …

Spontaneous neural synchrony links intrinsic spinal sensory and motor networks during unconsciousness

JG McPherson, MF Bandres - Elife, 2021 - elifesciences.org
Non-random functional connectivity during unconsciousness is a defining feature of
supraspinal networks. However, its generalizability to intrinsic spinal networks remains …

What has been learned from magnetic resonance imaging examination of the injured human spinal cord: a Canadian perspective

DW Cadotte, MA Akbar, MG Fehlings… - Journal of …, 2018 - liebertpub.com
Magnetic resonance imaging (MRI) has transformed the way surgeons and researchers
study and treat spinal cord injury. In this narrative review, we explore the historical context of …