Advanced heart failure: a position statement of the Heart Failure Association of the European Society of Cardiology

MG Crespo‐Leiro, M Metra, LH Lund… - European journal of …, 2018 - Wiley Online Library
This article updates the Heart Failure Association of the European Society of Cardiology
(ESC) 2007 classification of advanced heart failure and describes new diagnostic and …

[HTML][HTML] Uric acid and cardiovascular disease: a clinical review

Y Saito, A Tanaka, K Node, Y Kobayashi - Journal of cardiology, 2021 - Elsevier
Uric acid, the end-product of purine metabolism in humans, is not only a cause of gout, but
also may play roles in developing cardiovascular diseases such as hypertension, atrial …

JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure―digest version―

H Tsutsui, M Isobe, H Ito, K Okumura, M Ono… - Circulation …, 2019 - jstage.jst.go.jp
Heart Failure Society (JHFS). The working committee for this project includes members and
collaborators involved in the previous versions of the heart failure guidelines and members …

[HTML][HTML] Measurement and clinical significance of biomarkers of oxidative stress in humans

I Marrocco, F Altieri, I Peluso - Oxidative medicine and cellular …, 2017 - hindawi.com
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

[PDF][PDF] 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

P Ponikowski, AA Voors, SD Anker… - Kardiologia Polska …, 2016 - journals.viamedica.pl
5.2. 1. Ocena funkcji skurczowej lewej komory...................................... 1052 5.2. 2. Ocena
funkcji rozkurczowej lewej komory...................................... 1052 5.2. 3. Ocena funkcji prawej …

Innate immunity and the failing heart: the cytokine hypothesis revisited

DL Mann - Circulation research, 2015 - Am Heart Assoc
Elevated levels of inflammatory mediators have been identified in patients with heart failure,
including heart failure with reduced and preserved ejection fraction, as well as acute …

Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure: Refining the Gut Hypothesis

WHW Tang, Z Wang, Y Fan, B Levison… - Journal of the American …, 2014 - jacc.org
Background: Altered intestinal function is prevalent in patients with heart failure (HF), but its
role in adverse outcomes is unclear. Objectives: This study investigated the potential …

[HTML][HTML] Inflammation in human heart failure: major mediators and therapeutic targets

M Reina-Couto, P Pereira-Terra… - Frontiers in …, 2021 - frontiersin.org
Inflammation has been recognized as a major pathophysiological contributor to the entire
spectrum of human heart failure (HF), including HF with reduced ejection fraction, HF with …

Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications

T Münzel, T Gori, JF Keaney Jr, C Maack… - European heart …, 2015 - academic.oup.com
Systolic and diastolic myocardial dysfunction has been demonstrated to be associated with
an activation of the circulating and local renin–angiotensin–aldosterone system (RAAS), and …

Reactive oxygen species in cardiovascular disease

K Sugamura, JF Keaney Jr - Free radical biology and medicine, 2011 - Elsevier
Based on the “free radical theory” of disease, researchers have been trying to elucidate the
role of oxidative stress from free radicals in cardiovascular disease. Considerable data …