Aims Heart failure (HF) in the elderly carries a poor prognosis. We used the SENIORS
dataset of elderly HF patients aged≥ 70 years in order to develop a risk model for this …

There is intense interest in the identification of novel biomarkers which improve the
diagnosis of heart failure. Serum samples from 52 patients with systolic heart failure (EF< …

BACKGROUND: Hyperuricemia is associated with worse outcomes of patients with chronic
heart failure (HF). However, it is unknown in an unselected HF patients encountered in …

Background An association between uric acid (UA) and cardiovascular diseases, including
heart failure (HF), has been reported. However, whether UA is a causal risk factor for HF is …

Whether to treat hyperuricemia uncomplicated by articular gout, urolithiasis, or uric acid
nephropathy is an exercise in clinical judgment and universal agreement is lacking. Patients …

Aims This study aimed to determine the prognostic value of serum uric acid (SUA) on
outcomes in heart failure (HF) with preserved ejection fraction (HFpEF), and whether …

Chronic heart failure (CHF) remains an important and increasing public health care problem.
It is a complex syndrome affecting many body systems. Body wasting (ie, cardiac cachexia) …

Asymptomatic hyperuricaemia (HU) is considered a pathogenic factor in multiple disease
contexts, but a causative role is only proven for the crystalline form of uric acid in gouty …

More than 1100 articles now appear annually investigating “independent risk factors” or
“independent predictors” for various clinical outcomes. In medical research, independence …

Clinical studies have shown hyperuricemia strongly associated with insulin resistance as
well as cardiovascular disease. Direct evidence of how high uric acid (HUA) affects insulin …