The microbiome-shaping roles of bacteriocins
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …
[HTML][HTML] Towards the sustainable discovery and development of new antibiotics
An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
A bacterial pan-genome makes gene essentiality strain-dependent and evolvable
Many bacterial species are represented by a pan-genome, whose genetic repertoire far
outstrips that of any single bacterial genome. Here we investigate how a bacterial pan …
outstrips that of any single bacterial genome. Here we investigate how a bacterial pan …
Staphylococcal biofilms: Challenges and novel therapeutic perspectives
C Kranjec, D Morales Angeles, M Torrissen Mårli… - Antibiotics, 2021 - mdpi.com
Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …
the human microbiota. While being harmless in many cases, many virulence factors result in …
Host defense peptides: Dual antimicrobial and immunomodulatory action
M Drayton, JP Deisinger, KC Ludwig… - International Journal of …, 2021 - mdpi.com
The rapid rise of multidrug-resistant (MDR) bacteria has once again caused bacterial
infections to become a global health concern. Antimicrobial peptides (AMPs), also known as …
infections to become a global health concern. Antimicrobial peptides (AMPs), also known as …
β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium
JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division
Bacterial cell wall biosynthesis is the target of many important antibiotics. Its spatiotemporal
organization is closely coordinated with cell division. However, the role of peptidoglycan …
organization is closely coordinated with cell division. However, the role of peptidoglycan …
Polymyxin and lipopeptide antibiotics: membrane-targeting drugs of last resort
EVK Ledger, A Sabnis, AM Edwards - Microbiology, 2022 - microbiologyresearch.org
The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …
Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent bacterial
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …
Mechanisms of action of ionic liquids on living cells: The state of the art
P Kumari, VVS Pillai, A Benedetto - Biophysical reviews, 2020 - Springer
Ionic liquids (ILs) are a relatively new class of organic electrolytes composed of an organic
cation and either an organic or inorganic anion, whose melting temperature falls around …
cation and either an organic or inorganic anion, whose melting temperature falls around …