Recently, the human ATP-binding cassette transporter-1 (ABC1) gene has been
demonstrated to be mutated in patients with Tangier disease. To investigate the role of the …

ABCA1 mediates the secretion of cellular free cholesterol and phospholipids to an
extracellular acceptor, apolipoprotein AI, to form nascent high‐density lipoprotein (HDL) …

We performed a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,007 cases with high-pressure glaucoma (HPG) and 1,009 controls from southern China …

Cholesterol homeostasis is among the most intensely regulated processes in biology. Since
its isolation from gallstones at the time of the French Revolution, cholesterol has been …

Recent studies have identified the liver X receptors (LXRα and LXRβ) as important
regulators of cholesterol metabolism and transport. LXRs control transcription of genes …

ABCA1 (ATP-binding cassette transporter A1) is a major regulator of cholesterol efflux and
high density lipoprotein (HDL) metabolism. Mutations in human ABCA1 cause severe HDL …

In this paper, the cDNA microarray technique was used to investigate the gene expression
profiles of human fibroblasts irradiated by low-intensity red light. Proliferation assays …

A key issue in the immune system is to generate specific cell types, often with opposing
activities. The mechanisms of differentiation and subtype specification of immune cells such …

Rationale: Foam cell formation because of excessive accumulation of cholesterol by
macrophages is a pathological hallmark of atherosclerosis, the major cause of morbidity and …

Virtually every cell in the body restricts phosphatidylserine (PS) to the inner leaflet of the
plasma membrane by energy-dependent transport from the outer to the inner leaflet of the …