Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey

M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …

Novel SERS labels: Rational design, functional integration and biomedical applications

B Shan, Y Pu, Y Chen, M Liao, M Li - Coordination Chemistry Reviews, 2018 - Elsevier
Driven by the growing demand for healthcare and point-of-care test applications, next-
generation diagnostic tools of diseases require sensing platforms that enable rapid …

High-Mannose N-Glycans as Malignant Progression Markers in Early-Stage Colorectal Cancer

F Boyaval, H Dalebout, R Van Zeijl, W Wang… - Cancers, 2022 - mdpi.com
Simple Summary The detection of colorectal cancer (CRC) at an early stage is increasing
due to the implementation of screening programs. Local excision of early CRC is potentially …

Nanodiagnosis and nanotreatment of colorectal cancer: An overview

M Barani, M Bilal, A Rahdar, R Arshad, A Kumar… - Journal of Nanoparticle …, 2021 - Springer
The most suitable strategy to improving the long-term viability of cancer patients and
overcoming the high morbidity and severity of cancer is the precise identification of particular …

N-glycomic signature of stage II colorectal cancer and its association with the tumor microenvironment

F Boyaval, R Van Zeijl, H Dalebout, S Holst… - Molecular & Cellular …, 2021 - ASBMB
The choice for adjuvant chemotherapy in stage II colorectal cancer is controversial as many
patients are cured by surgery alone and it is difficult to identify patients with high risk of …

Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer

Y Li, Z Sun, B Liu, Y Shan, L Zhao, L Jia - Cell death & disease, 2017 - nature.com
Metastasis is a multistep molecular network process, which is the major cause of death in
patients with colorectal cancer (CRC). MicroRNAs (miRNAs) play pivotal roles in …

Genome-wide association study on immunoglobulin G glycosylation patterns

A Wahl, E Van den Akker, L Klaric, J Štambuk… - Frontiers in …, 2018 - frontiersin.org
Immunoglobulin G (IgG), a glycoprotein secreted by plasma B-cells, plays a major role in the
human adaptive immune response and are associated with a wide range of diseases …

Characterization of sialylation-related long noncoding RNAs to develop a novel signature for predicting prognosis, immune landscape, and chemotherapy response in …

M Zhou, S Lv, Y Hou, R Zhang, W Wang, Z Yan… - Frontiers in …, 2022 - frontiersin.org
Aberrant sialylation plays a key biological role in tumorigenesis and metastasis, including
tumor cell survival and invasion, immune evasion, angiogenesis, and resistance to therapy …

[HTML][HTML] Mass spectrometry-assisted gel-based proteomics in cancer biomarker discovery: approaches and application

R Huang, Z Chen, L He, N He, Z Xi, Z Li, Y Deng… - Theranostics, 2017 - ncbi.nlm.nih.gov
There is a critical need for the discovery of novel biomarkers for early detection and targeted
therapy of cancer, a major cause of deaths worldwide. In this respect, proteomic …

[HTML][HTML] Recent advances in the mass spectrometry methods for glycomics and cancer

MJ Kailemia, G Xu, M Wong, Q Li… - Analytical …, 2018 - ncbi.nlm.nih.gov
The review focuses on recent aspects (last three years) of glycosylation analyses that
provide relevant information about cancer. It includes recent development in glycan and …