The prevalence of arterial hypertension, particularly systolic hypertension, is constantly
rising worldwide. This is mainly the clinical expression of arterial stiffening as a result of the …

The purpose of this guideline is to present evidence-based and consensus-based
recommendations for the prevention and treatment of postoperative delirium. The …

Objective Polypharmacy is the concomitant use of several drugs by a single person, and it
increases the risk of adverse drug-related events in older adults. Little is known about the …

Abstract Purpose Adverse drug reactions (ADRs) represent a common and potentially
preventable cause of unplanned hospitalization, increasing morbidity, mortality, and …

Background The term potentially inadequate medication (PIM) is used to describe
substances that may be unsuitable for use in the elderly and should be avoided. The …

Background: Polypharmacy and related adverse consequences are common in the older
adults, especially mortality, but the causality of this relationship remains unclear. This meta …

Perioperative neurocognitive disorders (NCDs) refer to neurocognitive abnormalities
detected during the perioperative periods, including preexisting cognitive impairment …

In the general population, the use of prescription drugs increases with age. European data
show that 46% of the European population in the age group 45–54 years use prescribed …

ABSTRACT Introduction: Adverse drug reactions (ADRs) are a major health concern
worldwide. There are multiple causes of ADRs, some of which are preventable …

Background Multi-morbidity and polypharmacy increase the risk of non-trivial adverse drug
reactions (ADRs) in older people during hospitalization. Despite this, there are no …