Diet, lifestyle and cardiovascular diseases: linking pathophysiology to cardioprotective effects of natural bioactive compounds
J Sharifi-Rad, CF Rodrigues, F Sharopov… - International journal of …, 2020 - mdpi.com
Heart and blood vessels disorders comprise one of the main causes of death worldwide.
Pharmacologically active natural compounds have been used as a complementary therapy …
Pharmacologically active natural compounds have been used as a complementary therapy …
Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: a review
JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene), a polyphenol found in grapes, red wine,
peanuts, and apples, has been reported to exhibit a wide range of biological and …
peanuts, and apples, has been reported to exhibit a wide range of biological and …
[HTML][HTML] Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer
J Lee, JH You, MS Kim, JL Roh - Redox biology, 2020 - Elsevier
Ferroptosis is a newly defined form of cell death induced by iron-dependent accumulation of
lethal lipid peroxidation. Ferroptosis represent a therapeutic strategy to suppress therapy …
lethal lipid peroxidation. Ferroptosis represent a therapeutic strategy to suppress therapy …
[HTML][HTML] COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity
R Miller, AR Wentzel, GA Richards - Medical hypotheses, 2020 - Elsevier
The SARS-CoV-2 hyperinflammatory response is associated with high mortality. This
hypothesis suggests that a deficiency of nicotinamide adenine dinucleotide (NAD+) may be …
hypothesis suggests that a deficiency of nicotinamide adenine dinucleotide (NAD+) may be …
[HTML][HTML] Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity
New strategies to block the immune evasion activity of programmed death ligand-1 (PD-L1)
are urgently needed. When exploring the PD-L1-targeted effects of mechanistically diverse …
are urgently needed. When exploring the PD-L1-targeted effects of mechanistically diverse …
Role of plant-derived active constituents in cancer treatment and their mechanisms of action
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …
one of the main causes of death worldwide. Although substantial progress has been made …
[HTML][HTML] NF-κB inhibitors gifted by nature: The anticancer promise of polyphenol compounds
C Guan, X Zhou, H Li, X Ma, J Zhuang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Polyphenol compounds are natural antioxidants, which are rich in anti-inflammatory and
antioxidant components. They have a wide range of medicinal benefits that are believed to …
antioxidant components. They have a wide range of medicinal benefits that are believed to …
Recent advances in health benefits of stilbenoids
Biological targeting or molecular targeting is the main strategy in drug development and
disease prevention. However, the problem of “off-targets” cannot be neglected. Naturally …
disease prevention. However, the problem of “off-targets” cannot be neglected. Naturally …
Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review
Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …
Resveratrol's anti-cancer effects through the modulation of tumor glucose metabolism
Simple Summary The prevention and treatment of cancer is an ongoing medical challenge.
In the context of personalized medicine, the well-studied polyphenol resveratrol could …
In the context of personalized medicine, the well-studied polyphenol resveratrol could …