The plastic crisis requires drastic measures, especially for the plastics' end-of-life. Mixed
plastic fractions are currently difficult to recycle, but microbial metabolism might open new …

The transition from a fossil-based linear economy to a circular bioeconomy is no longer an
option but rather imperative, given worldwide concerns about the depletion of fossil …

Muconic acid is a bioprivileged molecule that can be converted into direct replacement
chemicals for incumbent petrochemicals and performance-advantaged bioproducts. In this …

Abstract Poly (ethylene terephthalate)(PET) is the most abundantly consumed synthetic
polyester and accordingly a major source of plastic waste. The development of …

CRISPR/Cas technologies constitute a powerful tool for genome engineering, yet their use
in non-traditional bacteria depends on host factors or exogenous recombinases, which limits …

Efficient genome engineering is critical to understand and use microbial functions. Despite
recent development of tools such as CRISPR-Cas gene editing, efficient integration of …

Expanding the portfolio of products that can be made from lignin will be critical to enabling a
viable bio-based economy. Here, we engineer Pseudomonas putida for high-yield …

Cross-linked elastomers are stretchable materials that typically are not recyclable or
biodegradable. Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) are soft and …

Efforts to produce aromatic monomers through catalytic lignin depolymerization have
historically focused on aryl–ether bond cleavage. A large fraction of aromatic monomers in …

Pseudomonas putida is a microbial chassis of huge potential for industrial and
environmental biotechnology, owing to its remarkable metabolic versatility and ability to …