Pancreatic cancer is a major cause of cancer-related death, but despondently, the outlook
and prognosis for this resistant type of tumor have remained grim for a long time. Currently, it …

Immune checkpoint blockade (ICB) approaches have changed the therapeutic landscape for
many tumor types. However, half of cutaneous squamous cell carcinoma (cSCC) patients …

The ubiquitin‑proteasome system is a major degradation pathway for> 80% of proteins in
vivo. Deubiquitylases, which remove ubiquitinated tags to stabilize substrate proteins, are …

Appropriate wavefront design can endow light fields with many useful properties, such as
accelerating, anti‐diffracting, self‐healing, and the capability to exhibit customizable …

Background The main reasons pancreatic cancer (PC) is difficult to treat are high tissue
fibrosis and a strong immunosuppressive microenvironment. Therefore, it is necessary to …