Effect of in utero and early-life conditions on adult health and disease
PD Gluckman, MA Hanson, C Cooper… - New England journal …, 2008 - Mass Medical Soc
Many lines of evidence, including epidemiologic data and extensive clinical and
experimental studies, indicate that early life events play a powerful role in influencing later …
experimental studies, indicate that early life events play a powerful role in influencing later …
Epidemiology of gestational diabetes mellitus and its association with Type 2 diabetes
A Ben‐Haroush, Y Yogev, M Hod - Diabetic medicine, 2004 - Wiley Online Library
Gestational diabetes (GDM) is defined as carbohydrate intolerance that begins or is first
recognized during pregnancy. Although it is a well‐known cause of pregnancy …
recognized during pregnancy. Although it is a well‐known cause of pregnancy …
Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on …
KJ Jenkins, A Correa, JA Feinstein, L Botto, AE Britt… - Circulation, 2007 - Am Heart Assoc
Prevention of congenital cardiovascular defects has been hampered by a lack of information
about modifiable risk factors for abnormalities in cardiac development. Over the past …
about modifiable risk factors for abnormalities in cardiac development. Over the past …
Diabetes mellitus and birth defects
OBJECTIVE: The purpose of this study was to examine associations between diabetes
mellitus and 39 birth defects. STUDY DESIGN: This was a multicenter case-control study of …
mellitus and 39 birth defects. STUDY DESIGN: This was a multicenter case-control study of …
Classification, epidemiology, and genetics of orofacial clefts
SE Watkins, RE Meyer… - Clinics in plastic …, 2014 - plasticsurgery.theclinics.com
There is considerable ambiguity in the use of terminology when referring to orofacial clefts
(OFCs). Many clinicians incorrectly refer to OFCs as deformities, which are said to be the …
(OFCs). Many clinicians incorrectly refer to OFCs as deformities, which are said to be the …
Spina bifida
LE Mitchell, NS Adzick, J Melchionne, PS Pasquariello… - The Lancet, 2004 - thelancet.com
Spina bifida results from failure of fusion of the caudal neural tube, and is one of the most
common malformations of human structure. The causes of this disorder are heterogeneous …
common malformations of human structure. The causes of this disorder are heterogeneous …
Aetiology of hypospadias: a systematic review of genes and environment
LFM Van der Zanden, I Van Rooij… - Human reproduction …, 2012 - academic.oup.com
BACKGROUND Hypospadias is a common congenital malformation of the male external
genitalia. Most cases have an unknown aetiology, which is probably a mix of monogenic …
genitalia. Most cases have an unknown aetiology, which is probably a mix of monogenic …
Consequences of fetal exposure to maternal diabetes in offspring
LS Fetita, E Sobngwi, P Serradas… - The Journal of …, 2006 - academic.oup.com
Context: Type 2 diabetes is the result of both genetic and environmental factors. Fetal
exposure to maternal diabetes is associated with a higher risk of abnormal glucose …
exposure to maternal diabetes is associated with a higher risk of abnormal glucose …
[HTML][HTML] What neonatal complications should the pediatrician be aware of in case of maternal gestational diabetes?
D Mitanchez, C Yzydorczyk, U Simeoni - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
In the epidemiologic context of maternal obesity and type 2 diabetes (T2D), the incidence of
gestational diabetes has significantly increased in the last decades. Infants of diabetic …
gestational diabetes has significantly increased in the last decades. Infants of diabetic …
Peri-conception hyperglycaemia and nephropathy are associated with risk of congenital anomaly in women with pre-existing diabetes: a population-based cohort …
R Bell, SV Glinianaia, PWG Tennant, RW Bilous… - Diabetologia, 2012 - Springer
Aims The aim of this study was to quantify the risk of major congenital anomaly, and to
assess the influence of peri-conception HbA 1c and other clinical and socio-demographic …
assess the influence of peri-conception HbA 1c and other clinical and socio-demographic …