Chronic kidney disease (CKD) is defined by kid-ney damage or a reduced kidney filtration
function with an estimated glomerular filtration rate< 60 mL/(min· 1.73 m²) for> 3 months …

Introduction Cardiovascular disease (CVD) is one of the global leading causes of morbidity
and mortality in chronic kidney disease (CKD) patients. Vascular calcification (VC) is a major …

In calcific aortic valve disease (CAVD), mechanosensitive valvular cells respond to fibrosis-
and calcification-induced tissue stiffening, further driving pathophysiology. No …

Chronic kidney disease (CKD) with high morbidity and mortality all over the world is
characterized by decreased kidney function, a condition which can result from numerous risk …

The crosstalk of the heart with distant organs such as the lung, liver, gut, and kidney has
been intensively approached lately. The kidney is involved in (1) the production of systemic …

Patients with chronic kidney disease (CKD) are at an increased cardiovascular risk
compared with the general population, which is driven, at least in part, by mechanisms that …

The prevalence of calcific aortic valve disease (CAVD) remains substantial while there is
currently no medical therapy available. Forkhead box O1 (FOXO1) is known to be involved …

Vascular calcification (VC) is a consequence of chronic kidney disease (CKD) which is of
paramount importance regarding the survival of CKD patients. VC is far from being …

Capsaicin, the organic compound which attributes the spicy flavor and taste of red peppers
and chili peppers, has been extensively studied for centuries as a potential natural remedy …

Chronic kidney disease patients are at increased risk of cardiovascular disease, which is the
leading cause of mortality among this population. In addition, chronic kidney disease is a …