Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …

Sex steroid hormones such as estrogens and androgens are involved in the development
and differentiation of the breast tissue. The activity and concentration of sex steroids is …

Background: The first evidence of micro-and nanoplastic (MNP) exposure in the human
placenta is emerging. However, the toxicokinetics and toxicity of MNPs in the placenta …

The estrous cycle is regulated by rhythmic endocrine interactions of the nervous and
reproductive systems, which coordinate the hormonal and ovulatory functions of the ovary …

Recent years have seen a dramatic improvement in protein-design methodology.
Nevertheless, most methods demand expert intervention, limiting their widespread adoption …

Nonalcoholic fatty liver disease (NAFLD) has become a worldwide epidemic and a major
public health problem, with a prevalence of approximately 25%. The pathogenesis of …

Breast cancer is the second most common malignancy in females worldwide and poses a
great challenge that necessitates the identification of novel therapeutic agents from several …

Introduction: Endometriosis is a chronic benign estrogen-dependent disease characterized
by the presence of endometriotic glands and stroma outside the uterine cavity. Although …

Sex-steroid hormones have been investigated for decades for their oncogenic properties in
hormone-dependent cancers. The increasing body of knowledge on the biological actions of …

Our understanding of the intracrine (or local) regulation of estrogen and other steroid
synthesis and degradation expanded in the last decades, also thanks to recent …