Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …

Vascular pathology is the second most common neuropathology of dementia after
Alzheimer's disease (AD), with small vessels disease (SVD) being considered the major …

Objective The aim of this study was to examine the putative adverse effects of ambient fine
particulate matter (PM2. 5: PM with aerodynamic diameters< 2.5 μm) on brain volumes in …

Inflammatory markers have been shown to predict neurocognitive outcomes in aging adults;
however, the degree to which peripheral markers mirror the central nervous system remains …

Background Vascular cognitive impairment (VCI) is a heterogeneous entity with multiple
aetiologies, all linked to underlying vascular disease. Among these, VCI related to …

We examined whether the pattern of middle-to late-life systemic inflammation was
associated with white matter (WM) structural abnormalities in older adults. A total of 1532 …

Background Chronic inflammation has been linked to memory and other cognitive
impairments, as well as Alzheimer's disease. Here, we investigate the association between …

Background/objectives Previous research suggests that everyday discrimination is
associated with worse episodic memory and partially mediates Black-White disparities in …

Breast cancer and its treatments are associated with mild cognitive impairment and brain
changes that could indicate an altered or accelerated brain aging process. We applied …

Objectives Non-Latino Black adults have greater risk for Alzheimer's dementia compared to
non-Latino White adults, possibly due to factors disproportionally affecting Black adults …