Patients with obesity have a high prevalence of nonalcoholic fatty liver disease (NAFLD),
representing a spectrum of simple steatosis to nonalcoholic steatohepatitis (NASH), without …

This review will summarize the metabolic effects of growth hormone (GH) on the adipose
tissue, liver, and skeletal muscle with focus on lipid and carbohydrate metabolism. The …

OBJECTIVE Age-associated insulin resistance may underlie the higher prevalence of type 2
diabetes in older adults. We examined a corollary hypothesis that obesity and level of …

Growth hormone (GH), a master regulator of somatic growth, also regulates carbohydrate
and lipid metabolism via complex interactions with insulin and insulin-like growth factor-1 …

Key points• Loss of muscle and tendon function during periods of immobilisation and
rehabilitation represents a challenge in clinical medicine.• It is not known to what extent …

Background Intrahepatocellular (IHCL) and intramyocellular (IMCL) lipids are ectopic lipid
stores. Aerobic exercise results in IMCL utilization in subjects over a broad range of exercise …

In addition to the subcutaneous and the visceral fat tissue, lipids can also be stored in non-
adipose tissue such as in hepatocytes (intrahepatocellular lipids; IHCL), skeletal …

Replacement of growth hormone (GH) in patients suffering from GH deficiency (GHD) offers
clinical benefits on body composition, exercise capacity, and skeletal integrity. However, GH …

Context: It is unclear whether the pattern of GH delivery to peripheral tissues has important
effects. Objective: The aim of the study was to compare the effects of pulsatile vs. continuous …

Growth hormone (GH) affects carbohydrate metabolism through direct negative effect on
insulin sensitivity and indirectly, via insulin-like growth factor-1 (IGF-1), which exerts positive …