Activated platelets and platelet-derived extracellular vesicles (EVs) have emerged as central
players in thromboembolic complications associated with severe coronavirus disease 2019 …

Extracellular cold-inducible RNA binding protein (eCIRP) is an inflammatory mediator that
causes inflammation and tissue injury in sepsis. Gasdermin D (GSDMD) is a protein that …

Anti-citrullinated protein antibodies (ACPAs) are autoantibodies commonly observed in
patients with rheumatoid arthritis (RA). Currently, most of the mechanisms of ACPA formation …

The role of high-mobility group box-1 (HMGB1) in outcome prediction in sepsis is
controversial. Furthermore, its association with necroptosis, a programmed cell necrosis …

SARS-CoV-2 is a member of the family of coronaviruses associated with severe outbreaks of
respiratory diseases in recent decades and is the causative agent of the COVID-19 …

Mycobacterium tuberculosis (Mtb) continues to pose a significant threat to global health
because it causes granulomas and systemic inflammatory responses during active …

Sepsis is one of the medical conditions with a high mortality rate and lacks specific treatment
despite several years of extensive research. Bacterial extracellular vesicles (bEVs) are …

Kidney disease is a major global health concern, affecting millions of people. Nephrologists
have shown interest in platelets because of coagulation disorders caused by renal diseases …

Sepsis is a life-threatening syndrome caused by a pathological host response to an infection
that eventually, if uncontrolled, leads to septic shock and ultimately, death. In sepsis, a …

The inflammatory response is one of the host's mechanisms to combat pathogens. Normal
and controlled inflammation can accelerate the clearance of pathogens. However, in sepsis …