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Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Background: After critical illness, new or worsening impairments in physical, cognitive,
and/or mental health function are common among patients who have survived. Who should …

Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Acute respiratory distress syndrome (ARDS) survivors experience a high prevalence of
cognitive impairment with concomitantly impaired functional status and quality of life, often …

Rationale: Diaphragm dysfunction worsens outcomes in mechanically ventilated patients,
but the clinical impact of potentially preventable changes in diaphragm structure and …

The role of NOD‐like receptor protein 3 (NLRP3)‐mediated pyroptosis in acute lung injury
(ALI) has been well identified previously. Stimulator of interferon genes (STING) is an …

Survival of critically unwell patients has improved in the last decade due to advances in
critical care medicine. Some of these survivors develop cognitive, psychiatric and/or physical …

Rationale: Research evaluating acute respiratory failure (ARF) survivors' outcomes after
hospital discharge has substantial heterogeneity in terms of the measurement instruments …

Outcomes after acute respiratory distress syndrome (ARDS) are similar to those of other
survivors of critical illness and largely affect the nerve, muscle, and central nervous system …