Hairy root cultures as a source of polyphenolic antioxidants: Flavonoids, stilbenoids and hydrolyzable tannins

J Malarz, K Michalska, YV Yudina, A Stojakowska - Plants, 2022 - mdpi.com
Due to their chemical properties and biological activity, antioxidants of plant origin have
gained interest as valuable components of the human diet, potential food preservatives and …

Nanotechnology-mediated delivery of resveratrol as promising strategy to improve therapeutic efficacy in triple negative breast cancer (TNBC): Progress and promises

J Ahmad, J Ahamad, MS Algahtani, A Garg… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Triple-negative breast cancer (TNBC) presents unique challenges in diagnosis
and treatment. Resveratrol exhibits potential as a therapeutic intervention against TNBC by …

Arachidin-1, a prenylated stilbenoid from peanut, enhances the anticancer effects of paclitaxel in triple-negative breast cancer cells

S Mohammadhosseinpour, A Weaver, M Sudhakaran… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is an aggressive type of cancer that
is challenging to treat due to the lack of hormonal receptors used to target cancer cells; due …

Induction of the prenylated stilbenoids arachidin-1 and arachidin-3 and their semi-preparative separation and purification from hairy root cultures of peanut (Arachis …

AR Sharma, G Gajurel, I Ahmed, K Roedel… - Molecules, 2022 - mdpi.com
Prenylated stilbenoids such as arachidin-1 and arachidin-3 are stilbene derivatives that
exhibit multiple pharmacological activities. We report an elicitation strategy using different …

Groundnut and tree nuts: a comprehensive review on their lipid components, phytochemicals, and nutraceutical properties

D Maestri - Critical Reviews in Food Science and Nutrition, 2023 - Taylor & Francis
The health benefits of nut consumption have been extensively demonstrated in
observational studies and intervention trials. Besides the high nutritional value, countless …

[HTML][HTML] The cancer preventive activity and mechanisms of prenylated resveratrol and derivatives

T Zhou, Y Jiang, B Zeng, B Yang - Current Research in Toxicology, 2023 - Elsevier
Resveratrol is regarded as neutraceuticals with multiple health benefits. The introduction of
prenyl can enhance the bioactivity. In this work, the cancer preventive activities and …

[HTML][HTML] Stilbenoid derivatives as potent inhibitors of HIF-1α-centric cancer metabolism under hypoxia

TH Han, J Lee, DS Harmalkar, H Kang, G Jin… - Biomedicine & …, 2024 - Elsevier
Abstract Hypoxia-inducible factor (HIF)-1α is a crucial transcription factor associated with
cancer metabolism and is regarded as a potent anticancer therapeutic strategy within the …

Regulation of hippo signaling mediated apoptosis by Rauvolfia tetraphylla in triple-negative breast cancer

B Balavaishnavi, M Kamaraj, TG Nithya, P Santhosh… - Medical Oncology, 2024 - Springer
Rauvolfia tetraphylla is an essential medicinal plant that has been widely used in traditional
medicine for various disease treatments. However, the tumor suppressor activity of R …

[HTML][HTML] Stilbene-rich extract increases the cytotoxic effects of paclitaxel in hormone receptor-positive and triple-negative breast cancer spheroids

S Mohammadhosseinpour, A Weaver… - Phytomedicine Plus, 2024 - Elsevier
Background Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer
that lacks three receptors commonly found in breast cancer cells. It is associated with high …

Integration of phenylalanine precursor feeding and elicitor treatment in concert with the cellulase-assisted extraction approach to improve stilbene compound …

C Tothong, C Pankaew, P Chayjarung… - Plant Cell, Tissue and …, 2023 - Springer
Abstract Trans-resveratrol, trans-arachidin-1 (Ara-1), and trans-arachidin-3 (Ara-3) are major
stilbene compounds found in elicited peanut hairy root culture and exert diverse potential …