Research progress on the prevention and treatment of hyperuricemia by medicinal and edible plants and its bioactive components

W Cheng-Yuan, D Jian-Gang - Frontiers in Nutrition, 2023 - frontiersin.org
Hyperuricemia is another common metabolic disease, which is considered to be closely
related to the development of many chronic diseases, in addition to the “three highs.” …

A systematic review on the research Progress on polysaccharides from fungal traditional Chinese medicine

C Bai, F Su, W Zhang, H Kuang - Molecules, 2023 - mdpi.com
Traditional Chinese medicine (TCM) is a class of natural drugs with multiple components
and significant therapeutic effects through multiple targets. It also originates from a wide …

Inhibition of intrarenal PRR-RAS pathway by Ganoderma lucidum polysaccharide peptides in proteinuric nephropathy

H Fang, X Li, D Lin, L Wang, T Yang, B Yang - International Journal of …, 2023 - Elsevier
Excessive proteinuria leads to renal dysfunction and damage. Ganoderma lucidum
polysaccharide peptide (GL-PP) and Ganoderma lucidum polysaccharide peptide 2 (GL …

Polysaccharide extracted from cultivated Sanghuangporous vaninii spores using three-phase partitioning with enzyme/ultrasound pretreatment: Physicochemical …

F Jiang, R Chen, C Tang, LQ Li, JK Yan… - International Journal of …, 2023 - Elsevier
Sanghuangporous vaninii, as a valuable dietary supplement and medicinal ingredient,
contains abundant bioactive polysaccharides that have health-promoting effects. In the …

Chinese Sumac (Rhus chinensis Mill.) Fruits Prevent Hyperuricemia and Uric Acid Nephropathy in Mice Fed a High-Purine Yeast Diet

N Ma, S Cai, Y Sun, C Chu - Nutrients, 2024 - mdpi.com
Hyperuricemia (HUA) is a prevalent chronic disease, characterized by excessive blood uric
acid levels, that poses a significant health risk. In this study, the preventive effects and …

Guluronate oligosaccharides exerts beneficial effects on hyperuricemia and regulation of gut microbiota in mice

B Wei, P Ren, C Xue, Y Wang, Q Tang - Food Bioscience, 2023 - Elsevier
Guluronate oligosaccharides (GOS) is a biologically active natural product derived from
brown algae. This study aimed to evaluate the amelioration of hyperuricemia and renal …

Peptide NCTX15 derived from spider toxin gland effectively relieves hyperuricemia in mice

Y Liu, N Liu, W Bian, Y Zhang, Y Wu, Y Peng… - Biochemical and …, 2023 - Elsevier
Hyperuricemia is a clinical disease characterized by a continuous increase in uric acid (UA)
due to purine metabolism disorder. As current drug treatments are limited, it is imperative to …

New insights into anti-hyperuricemic effects of novel peptides from Antarctic Krill (Euphausia superba) by Q-Exactive Orbitrap MS-based non-targeted metabolomics

L Hao, Y Ding, Y Fan, C Xia, Y Meng, Q Jia, J Zhang… - Food Bioscience, 2024 - Elsevier
Hyperuricemia (HUA) endangers renal function and induces gout. Although peptides from
Antarctic Krill (AKP) showed anti-hyperuricemic effects, the underlying mechanism remained …

Therapeutic potential of Ganoderma lucidum polysaccharide peptide in Doxorubicin-induced nephropathy: modulation of renin-angiotensin system and proteinuria

H Fang, D Lin, X Li, L Wang, T Yang - Frontiers in Pharmacology, 2023 - frontiersin.org
Introduction: In the Doxorubicin (DOX)-induced nephropathy model, proteinuria is a
manifestation of progressive kidney injury. The pathophysiology of renal illness is heavily …

TCM and related active compounds in the treatment of gout: the regulation of signaling pathway and urate transporter

X Sun, L Yang, H Sun, Y Sun, S Wei, Y Han… - Frontiers in …, 2023 - frontiersin.org
Gout represents a metabolic ailment resulting from the accumulation of monosodium urate
crystals within joints, causing both inflammation and, harm to tissues. The primary …