New world and old world Leishmania infections: a practical review

I Kevric, MA Cappel, JH Keeling - Dermatologic clinics, 2015 - derm.theclinics.com
Leishmaniasis is a tropical disease caused by an intracellular parasite of the genus
Leishmania. The vector of transmission is the sandfly, which deposits one of the 20 disease …

[HTML][HTML] Role of cytokines in experimental and human visceral leishmaniasis

M Samant, U Sahu, SC Pandey… - Frontiers in cellular and …, 2021 - frontiersin.org
Visceral Leishmaniasis (VL) is the most fatal form of disease leishmaniasis. To date, there
are no effective prophylactic measures and therapeutics available against VL. Recently, new …

Mechanisms of immune evasion in leishmaniasis

G Gupta, S Oghumu, AR Satoskar - Advances in applied microbiology, 2013 - Elsevier
Diseases caused by Leishmania present a worldwide problem, and current therapeutic
approaches are unable to achieve a sterile cure. Leishmania is able to persist in host cells …

Leishmania exosomes modulate innate and adaptive immune responses through effects on monocytes and dendritic cells

JM Silverman, J Clos, E Horakova… - The Journal of …, 2010 - journals.aai.org
We investigated the properties of leishmania exosomes with respect to influencing innate
and adaptive immune responses. Exosomes from Leishmania donovani modulated human …

[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

[PDF][PDF] Visceral leishmaniasis-current therapeutic modalities

S Sundar, M Chatterjee - Indian Journal of Medical Research, 2006 - researchgate.net
Major therapeutic obstacles in the treatment of visceral leishmaniasis (VL) include the
alarming increase in antimonial unresponsiveness especially in Bihar, India and relapses in …

Immune response to leishmania: paradox rather than paradigm

P Tripathi, V Singh, S Naik - FEMS Immunology & Medical …, 2007 - academic.oup.com
The leishmaniases are a group of diseases caused by protozoan parasites of the genus
Leishmania. Various Leishmania species can cause human infection, producing a spectrum …

Immunobiology of leishmaniasis

U Sharma, S Singh - 2009 - nopr.niscpr.res.in
Leishmaniasis is a parasitic disease caused by various species of Leishmania, a unicellular
kinetoplastid protozoan flagellate. It manifests mainly in 3 clinical forms; visceral …

Leishmania/HIV co-infections in the second decade

I Cruz, J Nieto, J Moreno, C Cañavate, P Desjeux… - 2006 - digital.csic.es
Leishmania-HIV co-infection has been globally controlled in Southern Europe since 1997
because of highly active anti retroviral therapy (HAART), but it appears to be an increasing …

Expression of IFN-γ, TNF-α, IL-10 and TGF-β in lymph nodes associates with parasite load and clinical form of disease in dogs naturally infected with Leishmania …

CF Alves, IFG de Amorim, EP Moura, RR Ribeiro… - Veterinary immunology …, 2009 - Elsevier
American visceral leishmaniasis is a zoonosis of the New World. Dogs are the main
reservoir of the disease and there is much interest in the understanding of mechanisms …