VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …

Placental malaria is caused by Plasmodium falciparum-infected erythrocytes (IEs) adhering
to chondroitin sulfate proteoglycans in placenta via VAR2CSA-type PfEMP1. Human …

Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been
tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively …

Placental accumulation of Plasmodium falciparum infected erythrocytes results in maternal
anemia, low birth weight, and pregnancy loss. The parasite protein VAR2CSA facilitates the …

Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies.
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …

Malaria and HIV are geographically in the tropics and subtropics of the world, including sub-
Saharan Africa. Understanding the overlapping effect of both infections, especially among …

Malaria during pregnancy is a major global health problem caused by infection with
Plasmodium falciparum parasites. Severe effects arise from the accumulation of infected …

Post-translational modifications (PTMs) are essential for regulating protein functions,
influencing various fundamental processes in eukaryotes. These include, but are not limited …

The issue of antibody cross-reactivity is of central importance in immunology, and not least
in protective immunity to Plasmodium falciparum malaria, where key antigens show …

The Plasmodium falciparum protein VAR2CSA allows infected erythrocytes to accumulate
within the placenta, inducing pathology and poor birth outcomes. Multiple exposures to …