Genomic instability is the hallmark of various cancers with the increasing accumulation of
DNA damage. The application of radiotherapy and chemotherapy in cancer treatment is …

Simple Summary The relationship between the immune system and tumours is currently one
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …

RNA methylation is a novel epigenetic modification that can be used to evaluate tumor
prognosis. However, the underlying mechanisms are unclear. This study aimed to …

Background The pivotal role of long noncoding RNAs (lncRNAs) in cancer immune
responses has been well established. This study was conducted with the aim of exploring …

Background To build a predictive scoring model based on simple immune and inflammatory
parameters to predict postoperative survival in patients with breast cancer. Methods We …

Myeloid-derived suppressor cells (MDSCs) are a group of heterogeneous cells which are
abnormally accumulated during the differentiation of myeloid cells. Immunosuppression is …

Lung adenocarcinoma (LUAD) is a common type of lung cancer with high frequent
metastasis and a high death rate. However, genes responsible for LUAD metastasis are still …

Simple Summary The manuscript reports the most recent literature regarding treatment with
ICIs in mCRC, focusing on dMMR/MSI-H and POLE-mutated tumors, discussing current …

RNA binding motif protein 15 (RBM15) is a key regulatory factor involved in N6-
methyladenosine (m6A) methylation. It has been reported that RBM15 plays an important …

As an important means of communication among cells, exosomes are being studied more
and more widely, especially in the context of cancer immunotherapy. In the phase of tumor …