Treatment of negative symptoms: where do we stand, and where do we go?

A Aleman, TM Lincoln, R Bruggeman, I Melle… - Schizophrenia …, 2017 - Elsevier
Negative symptoms, eg social withdrawal, reduced initiative, anhedonia and affective
flattening, are notoriously difficult to treat. In this review, we take stock of recent research into …

[HTML][HTML] Moderate effects of noninvasive brain stimulation of the frontal cortex for improving negative symptoms in schizophrenia: meta-analysis of controlled trials

A Aleman, S Enriquez-Geppert, H Knegtering… - Neuroscience & …, 2018 - Elsevier
Background Negative symptoms in schizophrenia concern a clinically relevant reduction of
goal-directed behavior that strongly and negatively impacts daily functioning. Existing …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

Neuroimaging and multiomics reveal cross-scale circuit abnormalities in schizophrenia

M Wang, H Yan, X Tian, W Yue, Y Liu, L Fan… - Nature Mental …, 2023 - nature.com
Schizophrenia (SCZ) is a highly heterogeneous disorder with diverse clinical manifestations
and macro-and microscale biological variations, usually observed at dissociable levels …

An exploration of loneliness experienced by people living with mental illness and the impact on their recovery journey: An integrative review

V Caple, P Maude, R Walter… - Journal of psychiatric and …, 2023 - Wiley Online Library
Accessible Summary What is known on the subject? There is evidence that social isolation
and loneliness is more prevalent in people living with mental illness than in the general …

[图书][B] Pragmatic disorders across the life span

L Cummings, L Cummings - 2014 - Springer
There is now an extensive empirical literature on the nature and extent of pragmatic
disorders in a range of clinical populations. This chapter attempts to organize the findings of …

Affective empathy in schizophrenia: a meta-analysis

KA Bonfils, PH Lysaker, KS Minor, MP Salyers - Schizophrenia research, 2016 - Elsevier
Background Affective empathy, or the emotional response one has to the experiences or
emotional states of others, contributes to relationship-maintaining behaviors and is key in …

A meta-analysis of the associations between theory of mind and neurocognition in schizophrenia

E Thibaudeau, AM Achim, C Parent, M Turcotte… - Schizophrenia …, 2020 - Elsevier
Abstract Theory of mind (ToM) refers to the ability to infer the mental states of others. ToM is
impaired in schizophrenia and these deficits seem to hinder functional recovery. ToM is thus …

Moving from efficacy to effectiveness in cognitive behavioral therapy for psychosis: a randomized clinical practice trial.

TM Lincoln, M Ziegler, S Mehl, ML Kesting… - Journal of consulting …, 2012 - psycnet.apa.org
Objective: Randomized controlled trials have attested the efficacy of cognitive behavioral
therapy (CBT) in reducing psychotic symptoms. Now, studies are needed to investigate its …

[HTML][HTML] From “under” to “over” social cognition in schizophrenia: is there distinct profiles of impairments according to negative and positive symptoms?

E Peyroux, Z Prost, C Danset-Alexandre… - Schizophrenia Research …, 2019 - Elsevier
Interactions between social cognition and symptoms of schizophrenia have been
investigated, but mostly component by component. Here we tested the assumption that two …