Urinary peptidomics focuses on endogenous urinary peptide content. Many studies now
show the usefulness of this approach for the discovery and validation of biomarkers in …

Chronic kidney disease (CKD) is an aging-related disorder that represents a major global
public health burden. Current biochemical biomarkers, such as serum creatinine and urinary …

Globally, chronic kidney disease (CKD) contributes substantial morbidity and mortality.
Recently, various 'omics platforms have provided insight into the molecular basis of kidney …

Chronic kidney disease (CKD) is a global public health problem that is associated with
excess morbidity, mortality, and health resource utilization. The progression of CKD is …

Background: This study aimed to analyze the scientific outputs of diabetic kidney disease
(DKD) research and explore its hotspots and frontiers from 2000 to 2017, using bibliometric …

Biomarker development, improvement, and clinical implementation in the context of kidney
disease have been a central focus of biomedical research for decades. To this point, only …

Renal fibrosis is a hallmark of chronic kidney disease (CKD) caused by an imbalance
between formation and degradation of extracellular matrix proteins. We investigated the …

Abstract Treatment effectiveness for kidney disease is limited by lack of accuracy, sensitivity,
specificity of diagnostic, prognostic, and therapeutic biomarkers. The gold standard test …

In this article, the benefits of urinary proteomics in comparison with kidney biopsy are
discussed. The majority of urinary proteins are generated by the kidney, hence the urinary …

Diabetic kidney disease is the most frequent cause of end-stage renal disease. This implies
failure of current therapeutic approaches based on renin-angiotensin system (RAS) …