The excessive formation of reactive oxygen species (ROS) and impairment of defensive
antioxidant systems leads to a condition known as oxidative stress. The main source of free …

Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …

Reactive oxygen species (ROS) and mitochondria play a pivotal role in regulating platelet
functions. Platelet activation determines a drastic change in redox balance and in platelet …

Chronic heart failure (CHF) is the final outcome of many cardiovascular diseases, and is a
severe health issue faced by the elderly population. Mixed lineage kinase 3 (MLK3), a …

Aging is characterized by a progressive decline in the normal physiological functions of an
organism, ultimately leading to mortality. Nicotinamide adenine dinucleotide (NAD+) is an …

Oxidative stress plays a key role in many physiological and pathological conditions. The
intracellular oxidative homeostasis is tightly regulated by the reactive oxygen species …

Age-related macular degeneration (AMD) is a complex eye disease that affects millions of
people worldwide and is the main reason for legal blindness and vision loss in the elderly in …

High altitude (hypobaric hypoxia) triggers several mechanisms to compensate for the
decrease in oxygen bioavailability. One of them is pulmonary artery vasoconstriction and its …

Sarcopenia is primarily characterized by skeletal muscle disturbances such as loss of
muscle mass, quality, strength, and physical performance. It is commonly seen in elderly …

Abstract Hexavalent chromium (Cr (VI)), the most toxic valence state of chromium, is widely
present in industrial effluents and wastes. Although previous study has reported that Cr (VI) …