An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …

A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

As inflammation in the brain contributes to several neurological and psychiatric diseases,
the cause of neuroinflammation is being widely studied. The causes of neuroinflammation …

The blood–brain barrier (BBB) is a dynamic platform for exchange of substances between
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …

Chronic, excessive neuroinflammation is a key feature of neurodegenerative diseases such
as Alzheimer's disease (AD) and Parkinson's disease (PD). However, neuroinflammatory …

Preclinical and clinical studies suggest that inflammation and vascular dysfunction
contribute to the pathogenesis of major depressive disorder (MDD). Chronic social stress …

The blood-brain barrier (BBB) mediates the communication between the periphery and the
central nervous system (CNS). Recently, CNS insulin resistance has been elucidated to play …

The blood–brain barrier (BBB) is a fundamental component of the central nervous system. Its
functional and structural integrity is vital in maintaining the homeostasis of the brain …