Interactions between erectile dysfunction, cardiovascular disease and cardiovascular drugs

D Terentes-Printzios, N Ioakeimidis, K Rokkas… - Nature Reviews …, 2022 - nature.com
Sexual health has a fundamental role in overall health and well-being, and a healthy and
dynamic sex life can make an important contribution to a good quality of life. Sexual …

Mechanisms of penile erection and basis for pharmacological treatment of erectile dysfunction

KE Andersson - Pharmacological reviews, 2011 - ASPET
Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents,
both autonomic and somatic, and supraspinal influences from visual, olfactory, and …

Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation

K Hatzimouratidis, E Amar, I Eardley, F Giuliano… - European urology, 2010 - Elsevier
CONTEXT: Erectile dysfunction (ED) and premature ejaculation (PE) are the two most
prevalent male sexual dysfunctions. OBJECTIVE: To present the updated version of 2009 …

Erectile dysfunction in the cardiovascular patient

C Vlachopoulos, G Jackson, C Stefanadis… - European heart …, 2013 - academic.oup.com
Erectile dysfunction is common in the patient with cardiovascular disease. It is an important
component of the quality of life and it also confers an independent risk for future …

Serum testosterone, testosterone replacement therapy and all‐cause mortality in men with type 2 diabetes: retrospective consideration of the impact of PDE5 inhibitors …

G Hackett, AH Heald, A Sinclair… - … journal of clinical …, 2016 - Wiley Online Library
Background Low testosterone levels occur in over 40% of men with type 2 diabetes mellitus
(T2 DM) and have been associated with increased mortality. Testosterone replacement …

Cardiovascular aspects of sexual medicine

G Jackson, P Montorsi, MA Adams… - The journal of sexual …, 2010 - academic.oup.com
Introduction Erectile dysfunction (ED) is common and considered to be predominantly of
vascular origin. Aim To evaluate the link between ED and coronary artery disease (CAD) …

The triad: erectile dysfunction-endothelial dysfunction-cardiovascular disease

C Vlachopoulos, N Ioakeimidis… - Current …, 2008 - ingentaconnect.com
Endothelial dysfunction is an important process in the development of atherosclerotic
cardiovascular disease, while it is also a major pathophysiological mechanism underlying …

Avanafil, a new rapid-onset phosphodiesterase 5 inhibitor for the treatment of erectile dysfunction

M Limin, N Johnsen, WJG Hellstrom - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Erectile dysfunction (ED) is a common sexual problem, affecting up
to half of men over 50 years of age. Phosphodiesterase type 5 (PDE5) inhibitors (sildenafil …

[HTML][HTML] Statin, testosterone and phosphodiesterase 5-inhibitor treatments and age related mortality in diabetes

G Hackett, PW Jones, RC Strange… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To determine how statins, testosterone (T) replacement therapy (TRT) and
phosphodiesterase 5-inhibitors (PDE5I) influence age related mortality in diabetic men …

Effectiveness and safety of phosphodiesterase 5 inhibitors in patients with cardiovascular disease and hypertension

SG Chrysant - Current hypertension reports, 2013 - Springer
Abstract Phosphodiesterase 5 (PDE 5) inhibitors are selective inhibitors of the enzyme PDE
5, which catalyzes the hydrolysis of cyclic guanosine monophosphate (cGMP), a potent …