Recent advances on the role of brain-derived neurotrophic factor (BDNF) in neurodegenerative diseases

KF Azman, R Zakaria - International journal of molecular sciences, 2022 - mdpi.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

Recent advances on the molecular mechanisms of exercise-induced improvements of cognitive dysfunction

Y Lu, FQ Bu, F Wang, L Liu, S Zhang, G Wang… - Translational …, 2023 - Springer
Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

[HTML][HTML] Intranasal delivery of BDNF-loaded small extracellular vesicles for cerebral ischemia therapy

X Zhou, X Deng, M Liu, M He, W Long, Z Xu… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stem cells (MSCs) have shown promise for the therapy of cerebral ischemia in
animal studies and clinical trials, yet their clinical application still faces many challenges …

[HTML][HTML] The role of brain derived neurotrophic factor in central nervous system

Y Li, F Li, D Qin, H Chen, J Wang, J Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Brain derived neurotrophic factor (BDNF) has multiple biological functions which are
mediated by the activation of two receptors, tropomyosin receptor kinase B (TrkB) receptor …

Possible antidepressant mechanisms of omega-3 polyunsaturated fatty acids acting on the central nervous system

L Zhou, JY Xiong, YQ Chai, L Huang, ZY Tang… - Frontiers in …, 2022 - frontiersin.org
Omega-3 polyunsaturated fatty acids (PUFAs) can play important roles in maintaining
mental health and resistance to stress, and omega-3 PUFAs supplementation can display …

The role of brain-derived neurotrophic factor in immune-related diseases: a narrative review

M Sochal, M Ditmer, A Gabryelska… - Journal of Clinical …, 2022 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is a neurotrophin regulating synaptic plasticity,
neuronal excitability, and nociception. It seems to be one of the key molecules in interactions …

Selenium ameliorates mercuric chloride-induced brain damage through activating BDNF/TrKB/PI3K/AKT and inhibiting NF-κB signaling pathways

LX Li, JH Chu, XW Chen, PC Gao, ZY Wang… - Journal of Inorganic …, 2022 - Elsevier
Abstract Mercuric chloride (HgCl 2), a heavy metal compound, causes neurotoxicity of
animals and humans. Selenium (Se) antagonizes heavy metal-induced organ damage with …

Serum BDNF as a potential biomarker of Alzheimer's disease: verification through assessment of serum, cerebrospinal fluid, and medial temporal lobe atrophy

Y Mori, M Tsuji, T Oguchi, K Kasuga, A Kimura… - Frontiers in …, 2021 - frontiersin.org
There is an urgent need to establish blood biomarkers for Alzheimer's disease (AD).
Although it has been speculated that brain-derived neurotrophic factor (BDNF) is associated …

Neurobiological highlights of cognitive impairment in psychiatric disorders

A Morozova, Y Zorkina, O Abramova… - International Journal of …, 2022 - mdpi.com
This review is focused on several psychiatric disorders in which cognitive impairment is a
major component of the disease, influencing life quality. There are plenty of data proving that …

The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways

H Kang, W Zhang, J Jing, D Huang, L Zhang… - Journal of Hazardous …, 2023 - Elsevier
The production of plastic is still increasing globally, which has led to an increasing number
of plastic particles in the environment. Nanoplastics (NPs) can penetrate the blood-brain …