Brain-derived neurotrophic factor as a biomarker in cancer-related cognitive impairment among adolescent and young adult cancer patients

DQ Ng, I Cheng, C Wang, CJ Tan, YL Toh, YQ Koh… - Scientific Reports, 2023 - nature.com
Brain-derived neurotrophic factor (BDNF) improves cognitive function by stimulating
neurogenesis and neuroplasticity. We hypothesize that higher plasma BDNF levels are …

Recreational ketamine-related deaths notified to the National Programme on Substance Abuse Deaths, England, 1997–2019

JM Corkery, WC Hung, H Claridge… - Journal of …, 2021 - journals.sagepub.com
Background: Ketamine is a phencyclidine derivative with dissociative anaesthetic properties.
Increasing numbers of individuals in England take ketamine recreationally. Information on …

The effects of ketogenic dietary therapies on sleep: A scoping review

L Pasca, CA Quaranta, S Grumi… - Journal of Sleep …, 2023 - Wiley Online Library
Sleep problems are common in neurological conditions for which ketogenic dietary
therapies (KDTs) are recognised as an effective intervention (drug‐resistant epilepsy, autism …

[HTML][HTML] Downregulation of fat mass and obesity-related protein in the anterior cingulate cortex participates in anxiety-and depression-like behaviors induced by …

XL Wang, X Wei, JJ Yuan, YY Mao, ZY Wang… - Frontiers in cellular …, 2022 - frontiersin.org
RNA N6-methyladenosine (m6A) modification represents another layer of gene regulation.
Fat mass and obesity-related protein (FTO) is the main N6-methyladenosine demethylase …

[HTML][HTML] The therapeutic effects of saikosaponins on depression through the modulation of neuroplasticity: From molecular mechanisms to potential clinical …

S Chen, K Wang, H Wang, Y Gao, K Nie, X Jiang… - Pharmacological …, 2024 - Elsevier
Depression is a major global health issue that urgently requires innovative and precise
treatment options. In this context, saikosaponin has emerged as a promising candidate …

Learning and memory impairment and transcriptomic profile in hippocampus of offspring after maternal fructose exposure during gestation and lactation

Y Zou, Q Guo, Y Chang, L Jia, L Zhai, Y Bai… - Food and Chemical …, 2022 - Elsevier
Increased fructose intake is a global issue, especially in mothers. Maternal fructose
exposure during gestation and lactation can affect learning and memory in offspring; …

Appropriate macronutrients or mineral elements are beneficial to improve depression and reduce the risk of depression

Z Quan, H Li, Z Quan, H Qing - International journal of molecular sciences, 2023 - mdpi.com
Depression is a common mental disorder that seriously affects the quality of life and leads to
an increasing global suicide rate. Macro, micro, and trace elements are the main …

Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice

F Huang, X Liu, S Xu, S Hu, S Wang, D Shi… - Frontiers in …, 2022 - frontiersin.org
Background Estrogen deficiency-induced depression is closely associated with an
imbalance in intestinal microbiota and inflammation. Prevotella histicola (P. histicola), an …

Intricate role of sleep deprivation in modulating depression: focusing on BDNF, VEGF, serotonin, cortisol, and TNF-α

S Vaseghi, A Mostafavijabbari, MS Alizadeh… - Metabolic Brain …, 2023 - Springer
In this review article, we aimed to discuss intricate roles of SD in modulating depression in
preclinical and clinical studies. Decades of research have shown the inconsistent effects of …

[HTML][HTML] How fish consumption prevents the development of Major Depressive Disorder? A comprehensive review of the interplay between n-3 PUFAs, LTP and BDNF

Ł Kołodziej, PL Czarny, S Ziółkowska, K Białek… - Progress in Lipid …, 2023 - Elsevier
MDD (major depressive disorder) is a highly prevalent mental disorder with a complex
etiology involving behavioral and neurochemical factors as well as environmental stress …