Improving Diagnostic Precision: Urine Proteomics Identifies Promising Biomarkers for Necrotizing Enterocolitis

S Mackay, LC Frazer, GK Bailey, CM Miller, Q Gong… - medRxiv, 2024 - medrxiv.org
Background: Necrotizing enterocolitis (NEC) is a severe intestinal disease that primarily
impacts preterm infants. Current diagnostic tools are inadequate, so urine proteomics was …

[HTML][HTML] Протективные факторы слизистой оболочки мочевого пузыря-ключ к новым подходам к терапии инфекции мочевых путей

ИН Захарова, ИМ Османов, АН Касьянова… - Российский вестник …, 2018 - cyberleninka.ru
Мочевой пузырь является уникальным органом, который подвержен воздействию
различных агрессивных факторов от механического растяжения до воздействия …

[HTML][HTML] Mechanizmy utrzymania sterylności układu moczowego

E Okrągła, K Szychowska, L Wolska - Postępy Higieny i Medycyny …, 2014 - phmd.pl
W warunkach prawidłowego funkcjonowania organizmu układ moczowy jest jałowy, wyjątek
stanowi ujście cewki moczowej. Poprzez cewkę moczową drobnoustroje mogą wnikać do …

[HTML][HTML] Peptidome Profiling of Bubalus bubalis Urine and Assessment of Its Antimicrobial Activity against Mastitis-Causing Pathogens

R Kumar, N Tyagi, A Nagpal, JK Kaushik, AK Mohanty… - Antibiotics, 2024 - mdpi.com
Urinary proteins have been studied quite exhaustively in the past, however, the small sized
peptides have remained neglected for a long time in dairy cattle. These peptides are the …

Mechanisms of urinary tract sterility maintenance

E Okrągła, K Szychowska, L Wolska - Postepy Higieny i Medycyny …, 2014 - europepmc.org
Physiologically, urine and the urinary tract are maintained sterile because of physical and
chemical properties of urine and the innate immune system's action. The urinary tract is …

[HTML][HTML] Interpretación de los tests de sospecha e inicio de la terapia antibiótica empírica en infecciones urinarias

N Kuster, L Robino - Archivos de Pediatría del Uruguay, 2020 - scielo.edu.uy
Introducción: las infecciones del tracto urinario (ITU) son motivo de consulta frecuente. Los
nitritos y la estearasa leucocitaria (EL) o leucocitos en orina son marcadores de sospecha …

Urine concentrations of human beta-defensins and ribonuclease 7 in urinary tract infection and asymptomatic bacteriuria

C Kjölvmark, P Åkesson, LI Påhlman - Diagnostic Microbiology and …, 2017 - Elsevier
Antimicrobial peptides (AMPs) provide a first line of defense against bacterial infections.
Here we report that urine levels of AMPs, locally produced in the urinary tract, are lower in …

3′ Untranslated Region Variants in DEFA5 Gene Associated with Susceptibility to Iga Nephropathy in the Chinese Han Population

H Peng, P Fan, Y Hong, J He, X Zeng, F Xu… - Biomarkers in …, 2022 - Taylor & Francis
Aim: To evaluate the association between single-nucleotide polymorphisms in the 3′
untranslated region of the DEFA5 gene and IgA nephropathy (IgAN) risk, the authors …

Recombinant expression of a novel antimicrobial peptide consisting of human α-defensin 5 and Mytilus coruscus mytilin-1 in Escherichia coli

Y Shan, Y Dong, D Jiang - Journal of the Korean Society for Applied …, 2015 - Springer
Antibiotic peptides are a battery of broad-spectrum antibacterial cationic polypeptides widely
distributed in the plant and animal kingdoms. Among them, the human defensins are the first …

DCHS1 DNA copy number loss associated with pediatric urinary tract infection risk

AH Qureshi, D Liang, J Canas, J Hooks… - Innate …, 2020 - journals.sagepub.com
Urinary tract infections (UTI), associated with vesicoureteral reflux (VUR), can lead to chronic
kidney disease. Genetic alterations in the innate immune defenses contribute to UTI risk. We …