[PDF][PDF] Effectiveness of zebrafish models in understanding human diseases—A review of models

M Adhish, I Manjubala - Heliyon, 2023 - cell.com
Understanding the detailed mechanism behind every human disease, disorder, defect, and
deficiency is a daunting task concerning the clinical diagnostic tools for patients. Hence, a …

Impact of pharmaceutical products on zebrafish: An effective tool to assess aquatic pollution

M Porretti, F Arrigo, G Di Bella, C Faggio - Comparative Biochemistry and …, 2022 - Elsevier
Overuse of pharmaceuticals products (PPs) and sometimes ineffective wastewater
purification systems have led to the accumulation of these residues in aquatic systems …

Berberine is a suppressor of Hedgehog signaling cascade in colorectal cancer

Q Sun, Q Tao, T Ming, S Tang, H Zhao, M Liu, H Yang… - Phytomedicine, 2023 - Elsevier
Background Colorectal cancer (CRC) is a malignant affliction that burdens people globally.
Overactivated Hedgehog signal is highly implicated in CRC pathogenesis. Phytochemical …

[HTML][HTML] Mechanistic insight into the adverse outcome of tire wear and road particle leachate exposure in zebrafish (Danio rerio) larvae

J Chang, M Jiao, Z Zhang, W Liu, W Li, P Xu… - Environment …, 2023 - Elsevier
Tire wear particles (TWP) have become the major microplastic pollution in China. Road
runoff containing TWP leachate can decrease the eye size and even induced mortality in the …

Developmental toxicity of TCBPA on the nervous and cardiovascular systems of zebrafish (Danio rerio): A combination of transcriptomic and metabolomics

W Liu, Y Pan, L Yang, Y Xie, X Chen, J Chang… - Journal of …, 2023 - Elsevier
Tetrachlorobisphenol A (TCBPA), a widely used halogenated flame retardant, is frequently
detected in environmental compartments and human samples. However, unknown …

Inflammation and Obesity: The Pharmacological Role of Flavonoids in the Zebrafish Model

C Russo, A Maugeri, L Musumeci, G De Sarro… - International journal of …, 2023 - mdpi.com
A Mediterranean-style diet is highly encouraged thanks to its healthy food pattern, which
includes valuable nutraceuticals such as polyphenols. Among these, flavonoids are …

Zebrafish as a model to study vascular elastic fibers and associated pathologies

M Hoareau, N El Kholti, R Debret… - International Journal of …, 2022 - mdpi.com
Many extensible tissues such as skin, lungs, and blood vessels require elasticity to function
properly. The recoil of elastic energy stored during a stretching phase is provided by elastic …

Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites

R Tsaryk, N Yucel, EV Leonard, N Diaz, O Bondareva… - Scientific reports, 2022 - nature.com
Endothelial cells (ECs) lining blood vessels are exposed to mechanical forces, such as
shear stress. These forces control many aspects of EC biology, including vascular tone, cell …

UV filter ethylhexyl salicylate affects cardiovascular development by disrupting lipid metabolism in zebrafish embryos

G Zhao, M Gao, S Guo, S Zeng, C Ye, M Wang… - Science of The Total …, 2023 - Elsevier
Ethylhexyl salicylate (EHS) is an organic UV filter commonly used in sunscreens to protect
people from the UV radiation. The widespread use of EHS will enter the aquatic environment …

The zebrafish model system for dyslipidemia and atherosclerosis research: Focus on environmental/exposome factors and genetic mechanisms

M Vasyutina, A Alieva, O Reutova, V Bakaleiko… - Metabolism, 2022 - Elsevier
Dyslipidemias and atherosclerosis play a pivotal role in cardiovascular risk and disease.
Although some pathophysiological mechanisms underlying these conditions have been …