Angiotensin II receptor blockers (ARBs, collectively called sartans) are widely used
compounds therapeutically effective in cardiovascular disorders, renal disease, the …

The effects of brain AngII (angiotensin II) depend on AT1 receptor (AngII type 1 receptor)
stimulation and include regulation of cerebrovascular flow, autonomic and hormonal …

Metabolic syndrome is a disorder based on insulin resistance. Metabolic syndrome is
diagnosed by a co-occurrence of three out of five of the following medical conditions …

Beyond blood pressure control, angiotensin receptor blockers reduce common injury
mechanisms, decreasing excessive inflammation and protecting endothelial and …

Angiotensin II (Ang II), which is elevated in many chronic disease states such as end-stage
renal disease and congestive heart failure, induces cachexia and skeletal muscle wasting …

Background. To compare the tolerability and safety of telmisartan±hydrochlorothiazide
(HCTZ). Methods. This retrospective analysis was performed on all hypertensive patients …

Oxidative stress induced by hyperuricemia is closely associated with the renin‐angiotensin
system, as well as the onset and progression of cardiovascular disease (CVD) and chronic …

Angiotensin II activates two distinct receptors, the angiotensin II receptors type 1 (AT1) and
type 2 (AT2). In rodents, two AT1 subtypes were identified (AT1a and AT1b). To determine …

The definition of the Metabolic Syndrome (MS) has encountered difficulty in reaching a
universal consensus although there exists an agreement of its main pathologies which are …

Because all clinically approved angiotensin-receptor blockers (ARBs) have good safety
profiles and share the ability to block angiotensin II type 1 (AT1) receptors and reduce blood …