Cytotoxicity of dendrimers

A Janaszewska, J Lazniewska, P Trzepiński… - Biomolecules, 2019 - mdpi.com
Drug delivery systems are molecular platforms in which an active compound is packed into
or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the …

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model

S Kannan, H Dai, RS Navath, B Balakrishnan… - Science translational …, 2012 - science.org
Cerebral palsy (CP) is a chronic childhood disorder with no effective cure.
Neuroinflammation, caused by activated microglia and astrocytes, plays a key role in the …

Dendrimer nanoparticles for colorectal cancer applications

MR Carvalho, RL Reis, JM Oliveira - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Cancer nanotechnology is a prolific field of research, where nanotools are employed to
diagnose and treat cancer with unprecedented precision. Targeted drug delivery is …

Advances in the chemistry of dendrimers

M Sowinska, Z Urbanczyk-Lipkowska - New Journal of Chemistry, 2014 - pubs.rsc.org
Dendrimers, which are highly branched, multivalent and monodisperse polymers, have
received continuous interest in recent years because of the global demand for new …

Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment

N Amreddy, A Babu, J Panneerselvam… - … , Biology and Medicine, 2018 - Elsevier
Co-administration of functionally distinct anti-cancer agents has emerged as an efficient
strategy in lung cancer treatment. However, a specially designed drug delivery system is …

Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration

R Iezzi, BR Guru, IV Glybina, MK Mishra, A Kennedy… - Biomaterials, 2012 - Elsevier
Retinal neuroinflammation, mediated by activated microglia, plays a key role in the
pathogenesis of photoreceptor and retinal pigment epithelial cell loss in age-related macular …

Injectable nanomaterials for drug delivery: carriers, targeting moieties, and therapeutics

DM Webster, P Sundaram, ME Byrne - European Journal of Pharmaceutics …, 2013 - Elsevier
Therapeutics such as nucleic acids, proteins/peptides, vaccines, anti-cancer, and other
drugs have disadvantages of low bio-availability, rapid clearance, and high toxicity. Thus …

Advances in combination therapies based on nanoparticles for efficacious cancer treatment: an analytical report

S Mignani, M Bryszewska… - …, 2015 - ACS Publications
The main objective of nanomedicine research is the development of nanoparticles as drug
delivery systems or drugs per se to tackle diseases as cancer, which are a leading cause of …

[HTML][HTML] Metal-dendrimer hybrid nanomaterials for sensing applications

T Fernandes, AL Daniel-da-Silva, T Trindade - Coordination Chemistry …, 2022 - Elsevier
The nanochemical routes introduced in recent years have delivered important tools for the
preparation of multifunctional nanomaterials with the potential to be used in a variety of …