The eye is regarded as an immune privileged site. Since the presence of a vasculature
would impair vision, the vasculature of the eye is located outside of the central light path. As …

Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of
irreversible blindness in the developed world. DR arises as the result of prolonged …

Retinoid X receptors (RXRs) present a subgroup of the nuclear receptor superfamily with
particularly high evolutionary conservation of ligand binding domain. The receptor exists in …

Affecting nearly 80 million individuals, glaucoma is the number one cause of irreversible
blindness in the world. This ocular disease describes a set of optic neuropathies of which …

The rate at which obesity is becoming an epidemic in many countries is alarming. Obese
individuals have a high risk of developing elevated intraocular pressure and glaucoma …

Glaucoma is a common optic neuropathy disease affecting over 76 million people. Both
timely diagnosis and progression monitoring are critical but challenging. Conventional …

Myocilin is highly expressed in the trabecular meshwork (TM), which plays an important role
in the regulation of intraocular pressure (IOP). Myocilin abnormalities may cause dysfunction …

Simple Summary Glaucoma is a devastating eye disease causing progressive vision loss
and consequent irreversible blindness. The global prevalence of glaucoma is estimated at …

Aqueous humor (AH) can be easily and safely used to evaluate disease-specific biomarkers
in ocular disease. The aim of this study was to identify specific proteins biomarkers in the AH …

Glaucoma of which primary open angle glaucoma (POAG) constitutes 75%, is the second
leading cause of blindness. Elevated intra ocular pressure and Nitric oxide synthase (NOS) …