Microfluidic paper-based analytical devices (μPADs) have garnered significant interest as a
promising analytical platform in the past decade. Compared with traditional microfluidics …

Bioluminescence is the fascinating natural phenomenon by which living creatures produce
light. Bioluminescence occurs when the oxidation of a small-molecule luciferin is catalysed …

There are 20200 possible amino-acid sequences for a 200-residue protein, of which the
natural evolutionary process has sampled only an infinitesimal subset. De novo protein …

Proteins with desired functions and properties are important in fields like nanotechnology
and biomedicine. De novo protein design enables the production of previously unseen …

Monitoring of human serum albumin (HSA) in a point‐of‐care fashion is urgently needed in
particular for elderly or chronically ill patients. Herein, a dual‐state emissive chalcone probe …

The emergence of the smartphones has brought extensive changes to our lifestyles, from
communicating with one another, to shopping and enjoyment of entertainment, and from …

Synthetic biology is the discipline of engineering application-driven biological functionalities
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …

Highlights•SpyTag and SpyCatcher are peptide–protein partners that lock together
covalently.•Reaction occurs in a wide range of protein contexts, buffers and …

The field of protein design has made remarkable progress over the past decade. Historically,
the low reliability of purely structure-based design methods limited their application, but …

Heterogeneous immunoassays such as ELISA have become indispensable in modern
bioanalysis, yet translation into point-of-care assays is hindered by their dependence on …