[HTML][HTML] mRNA vaccines in disease prevention and treatment

G Zhang, T Tang, Y Chen, X Huang… - Signal transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …

Global prevalence of traumatic non-fatal limb amputation

CL McDonald, S Westcott-McCoy… - Prosthetics and …, 2021 - journals.lww.com
Background: Reliable information on both global need for prosthetic services and the current
prosthetist workforce is limited. Global burden of disease estimates can provide valuable …

Poverty, depression, and anxiety: Causal evidence and mechanisms

M Ridley, G Rao, F Schilbach, V Patel - Science, 2020 - science.org
BACKGROUND Depression and anxiety disorders are together responsible for 8% of years
lived with disability globally. Contrary to widely held preconceptions, these are not diseases …

Global, regional, and national burden of ischaemic heart disease and its attributable risk factors, 1990–2017: results from the Global Burden of Disease Study 2017

H Dai, AA Much, E Maor, E Asher… - … Journal-Quality of …, 2022 - academic.oup.com
Aims The aim of this study was to estimate the burden and risk factors for ischaemic heart
disease (IHD) in 195 countries and territories from 1990 to 2017. Methods and results Data …

[HTML][HTML] The prevalence of depression, anxiety and stress and their associated factors in college students

E Ramón-Arbués, V Gea-Caballero… - International journal of …, 2020 - mdpi.com
Aim: To estimate the prevalence of symptoms of depression, anxiety, stress and associated
factors in a population of college students. Method: Cross-sectional study of psychological …

[HTML][HTML] Ambient and household PM2. 5 pollution and adverse perinatal outcomes: A meta-regression and analysis of attributable global burden for 204 countries and …

R Ghosh, K Causey, K Burkart, S Wozniak… - PLoS …, 2021 - journals.plos.org
Background Particulate matter< 2.5 micrometer (PM2. 5) is associated with adverse
perinatal outcomes, but the impact on disease burden mediated by this pathway has not …

[HTML][HTML] Chondrocyte ferroptosis contribute to the progression of osteoarthritis

X Yao, K Sun, S Yu, J Luo, J Guo, J Lin, G Wang… - Journal of orthopaedic …, 2021 - Elsevier
Background Osteoarthritis (OA) is a complex process comprised of mechanical load,
inflammation, and metabolic factors. It is still unknown that if chondrocytes undergo …

Global, regional, and national burden of neck pain in the general population, 1990-2017: systematic analysis of the Global Burden of Disease Study 2017

S Safiri, AA Kolahi, D Hoy, R Buchbinder… - bmj, 2020 - bmj.com
Objective To use data from the Global Burden of Disease Study between 1990 and 2017 to
report the rates and trends of point prevalence, annual incidence, and years lived with …

Safety and efficacy of galcanezumab in patients for whom previous migraine preventive medication from two to four categories had failed (CONQUER): a multicentre …

WM Mulleners, BK Kim, MJA Láinez… - The Lancet …, 2020 - thelancet.com
Background Many patients who require migraine preventive treatment have not been able to
tolerate or have not responded to multiple previous preventive medications. We aimed to …

Prevalence, deaths, and disability‐adjusted life years due to musculoskeletal disorders for 195 countries and territories 1990–2017

S Safiri, AA Kolahi, M Cross, C Hill… - Arthritis & …, 2021 - Wiley Online Library
Objective To report the levels and trends of prevalence, deaths, and disability‐adjusted life
years (DALYs) due to musculoskeletal disorders, categorized as low back pain, neck pain …