Ruthenium complexes as antimicrobial agents

F Li, JG Collins, FR Keene - Chemical Society Reviews, 2015 - pubs.rsc.org
One of the major advances in medical science has been the development of antimicrobials;
however, a consequence of their widespread use has been the emergence of drug-resistant …

Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

MR Gill, JA Thomas - Chemical Society Reviews, 2012 - pubs.rsc.org
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …

Nanocatalytic innate immunity activation by mitochondrial DNA oxidative damage for tumor‐specific therapy

H Jiang, Y Guo, C Wei, P Hu, J Shi - Advanced Materials, 2021 - Wiley Online Library
The innate immune system plays a key role in protecting the human body from tumors,
which, unfortunately, is largely counteracted by their immune‐suppression function. Such an …

Near infrared-assisted Fenton reaction for tumor-specific and mitochondrial DNA-targeted photochemotherapy

P Hu, T Wu, W Fan, L Chen, Y Liu, D Ni, W Bu, J Shi - Biomaterials, 2017 - Elsevier
The strong dependence on oxygen level, low ultraviolet/visible (UV/vis) light penetration
depth and the extremely short lifetime of reactive oxygen species (ROS) are the major …

Strategies for the nuclear delivery of metal complexes to cancer cells

M Huynh, R Vinck, B Gibert, G Gasser - Advanced Materials, 2024 - Wiley Online Library
The nucleus is an essential organelle for the function of cells. It holds most of the genetic
material and plays a crucial role in the regulation of cell growth and proliferation. Since …

DNA-binding of nickel (II), copper (II) and zinc (II) complexes: Structure–affinity relationships

G Barone, A Terenzi, A Lauria, AM Almerico… - Coordination Chemistry …, 2013 - Elsevier
Abstract Nickel (II), copper (II) and zinc (II) complexes with the same ligands normally display
analogous coordination geometry and binding mode toward DNA. However, although …

Recent advances in luminescent heavy metal complexes for sensing

DL Ma, VPY Ma, DSH Chan, KH Leung, HZ He… - Coordination Chemistry …, 2012 - Elsevier
Luminescent metal complexes have attracted increasing attention in the literature over the
last few decades. In particular, transition metal compounds have been widely studied for …

Mesoporous silica/organosilica nanoparticles: Synthesis, biological effect and biomedical application

B Yang, Y Chen, J Shi - Materials Science and Engineering: R: Reports, 2019 - Elsevier
The interdisciplinary integration among material science, nanotechnology and biology has
been promoting the emergences of a large number of feasible nanoplatforms for diverse …

Recent studies on the antimicrobial activity of transition metal complexes of groups 6–12

S Nasiri Sovari, F Zobi - Chemistry, 2020 - mdpi.com
Antimicrobial resistance is an increasingly serious threat to global public health that requires
innovative solutions to counteract new resistance mechanisms emerging and spreading …

Targeting nucleus DNA with a cyclometalated dipyridophenazineruthenium (II) complex

H Huang, P Zhang, B Yu, Y Chen, J Wang… - Journal of Medicinal …, 2014 - ACS Publications
Recently, coordinatively saturated and substitutionally inert Ru (II) complexes have been
investigated as anticancer agents. Herein a cyclometalated Ru (II) complex,[Ru …