Smart biomaterials for articular cartilage repair and regeneration

Z Gu, J Wang, Y Fu, H Pan, H He… - Advanced Functional …, 2023 - Wiley Online Library
Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

[HTML][HTML] Inflammation and lymphatic function

S Schwager, M Detmar - Frontiers in immunology, 2019 - frontiersin.org
The lymphatic vasculature plays a crucial role in regulating the inflammatory response by
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …

[HTML][HTML] Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage

J Chen, L Wang, H Xu, L Xing, Z Zhuang… - Nature …, 2020 - nature.com
Extravasated erythrocytes in cerebrospinal fluid (CSF) critically contribute to the
pathogenesis of subarachnoid hemorrhage (SAH). Meningeal lymphatics have been …

[HTML][HTML] Nanoparticle–cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy

X Li, B Dai, J Guo, L Zheng, Q Guo, J Peng, J Xu… - Nano-micro letters, 2021 - Springer
Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …

[HTML][HTML] Current understanding of osteoarthritis pathogenesis and relevant new approaches

L Tong, H Yu, X Huang, J Shen, G Xiao, L Chen… - Bone research, 2022 - nature.com
Osteoarthritis (OA) is the most common degenerative joint disease that causes painful
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …

[HTML][HTML] The emerging importance of lymphatics in health and disease: an NIH workshop report

BJ Mehrara, AJ Radtke, GJ Randolph… - The Journal of …, 2023 - Am Soc Clin Investig
The lymphatic system (LS) is composed of lymphoid organs and a network of vessels that
transport interstitial fluid, antigens, lipids, cholesterol, immune cells, and other materials in …

Nanocarriers transport across the gastrointestinal barriers: the contribution to oral bioavailability via blood circulation and lymphatic pathway

D Wang, Q Jiang, Z Dong, T Meng, F Hu, J Wang… - Advanced Drug Delivery …, 2023 - Elsevier
Oral administration is the preferred route of drug delivery in clinical practice due to its
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …

Lymphatic targeting by albumin-hitchhiking: applications and optimisation

M Abdallah, OO Müllertz, IK Styles, A Mörsdorf… - Journal of Controlled …, 2020 - Elsevier
The lymphatic system plays an integral role in the development and progression of a range
of disease conditions, which has impelled medical researchers and clinicians to design …

Bacterial septic arthritis of the adult native knee joint: a review

JG Elsissy, JN Liu, PJ Wilton, I Nwachuku… - JBJS …, 2020 - journals.lww.com
Bacterial Septic Arthritis of the Adult Native Knee Joint: A... : JBJS Reviews Bacterial Septic
Arthritis of the Adult Native Knee Joint: A Review : JBJS Reviews JBJS Journal Case Connector …

[HTML][HTML] Development and aging of the lymphatic vascular system

A González-Loyola, TV Petrova - Advanced Drug Delivery Reviews, 2021 - Elsevier
The lymphatic vasculature has a pivotal role in regulating body fluid homeostasis, immune
surveillance and dietary fat absorption. The increasing number of in vitro and in vivo studies …