Management of residual risk after statin therapy

C Reith, J Armitage - Atherosclerosis, 2016 - Elsevier
Cardiovascular disease (CVD) is the leading cause of mortality worldwide. Observational
data indicate that low-density lipoprotein cholesterol (LDL-C) levels are strongly positively …

[HTML][HTML] Management of nonalcoholic fatty liver disease: an evidence-based clinical practice review

JP Arab, R Candia, R Zapata, C Muñoz… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To build a consensus among Chilean specialists on the appropriate management of
patients with nonalcoholic fatty liver disease (NAFLD) in clinical practice. METHODS …

Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1−/− mice

ED Labonté, LM Camarota, JC Rojas… - American Journal …, 2008 - journals.physiology.org
The impact of NPC1L1 and ezetimibe on cholesterol absorption are well documented.
However, their potential consequences relative to absorption and metabolism of other …

Atherogenic dyslipidemia in metabolic syndrome and type 2 diabetes: therapeutic options beyond statins

A Tenenbaum, EZ Fisman, M Motro, Y Adler - Cardiovascular diabetology, 2006 - Springer
Lowering of low-density lipoprotein cholesterol with 3-hydroxy-3-methylglutaryl coenzyme A
reductase inhibitors (statins) is clearly efficacious in the treatment and prevention of …

Ezetimibe alone or in combination with simvastatin increases small dense low-density lipoproteins in healthy men: a randomized trial

K Berneis, M Rizzo, HK Berthold… - European heart …, 2010 - academic.oup.com
Aims The predominance of small dense low-density lipoproteins (sdLDLs) has been
associated with increased cardiovascular risk. The effect of ezetimibe on LDL subfraction …

Anti-Obesity Effect of Auricularia delicate Involves Intestinal-Microbiota-Mediated Oxidative Stress Regulation in High-Fat-Diet-Fed Mice

L Li, S Zhai, R Wang, F Kong, A Yang, C Wang, H Yu… - Nutrients, 2023 - mdpi.com
Auricularia delicate (ADe), an edible fungus belonging to the family Auriculariaceae and
order Auriculariales, possesses antimicrobial, hepatoprotective, and antioxidant effects. In …

Reaching goal in hypercholesterolaemia: dual inhibition of cholesterol synthesis and absorption with simvastatin plus ezetimibe

SS Daskalopoulou, DP Mikhailidis - Current medical research and …, 2006 - Taylor & Francis
Lowering serum cholesterol levels reduces the risk of coronary heart disease (CHD)-related
events. Statins are commonly prescribed as first-line treatment but many patients at high-risk …

Update on the efficacy and safety of combination ezetimibe plus statin therapy

PP Toth, A Catapano, JE Tomassini… - Clinical Lipidology …, 2010 - search.proquest.com
The primary aim of lipid-related cardiovascular disease (CVD) risk management is the
lowering of LDL-C levels. Numerous studies have shown that statins, which inhibit …

Optimal management of combined dyslipidemia: what have we behind statins monotherapy?

A Tenenbaum, EZ Fisman, M Motro… - … : Clinical, Metabolic and …, 2008 - karger.com
Evidence of the effectiveness of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
(statins) within continuum of atherothrombotic conditions and particularly in the treatment …

The safety of ezetimibe and simvastatin combination for the treatment of hypercholesterolemia

AA Kei, TD Filippatos, MS Elisaf - Expert Opinion on Drug Safety, 2016 - Taylor & Francis
Introduction: In the light of the most recent and stricter dyslipidemia treatment guidelines, the
need for combination hypolipidemic therapy is increasing. Ezetimibe plus simvastatin is …