Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the Lys-Egfp-ki mouse model
SG Thawer, L Mawhinney, K Chadwick… - Journal of …, 2013 - Elsevier
The role of hematogenous (hMΦ) and microglial (mMΦ) macrophages following spinal cord
injury (SCI) remains unclear as they are not distinguished easily from each other in the …
injury (SCI) remains unclear as they are not distinguished easily from each other in the …
Acute in vivo exposure to interferon-γ enables resident brain dendritic cells to become effective antigen presenting cells
A Gottfried-Blackmore, UW Kaunzner… - Proceedings of the …, 2009 - National Acad Sciences
Dendritic cells (DC) are the professional antigen presenting cells (APC) that bridge the
innate and adaptive immune system. Previously, in a CD11c/EYFP transgenic mouse …
innate and adaptive immune system. Previously, in a CD11c/EYFP transgenic mouse …
Iba1+/NG2+ Macrophage-Like Cells Expressing a Variety of Neuroprotective Factors Ameliorate Ischemic Damage of the Brain
A Smirkin, H Matsumoto, H Takahashi… - Journal of Cerebral …, 2010 - journals.sagepub.com
In a transient 90-min middle cerebral artery occlusion (MCAO) model of rats, a large
ischemic lesion is formed where macrophage-like cells massively accumulate, many of …
ischemic lesion is formed where macrophage-like cells massively accumulate, many of …
Brain progranulin expression in GRN-associated frontotemporal lobar degeneration
AS Chen-Plotkin, J Xiao, F Geser, M Martinez-Lage… - Acta …, 2010 - Springer
Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is characterized by
progressive decline in behavior, executive function, and language. Progranulin (GRN) gene …
progressive decline in behavior, executive function, and language. Progranulin (GRN) gene …
Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct …
H Jyonouchi, L Geng, DL Streck, GA Toruner - Journal of …, 2011 - Elsevier
Innate/adaptive immune responses and transcript profiles of peripheral blood monocytes
were studied in ASD children who exhibit fluctuating behavioral symptoms following …
were studied in ASD children who exhibit fluctuating behavioral symptoms following …
CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species
YA Yeo, JM Martínez Gómez, JL Croxford… - Journal of …, 2012 - Springer
Abstract CD137 (4-1BB, TNFRSF9), a member of the tumor necrosis factor (TNF) receptor
family, is a potent T cell co-stimulatory molecule. CD137 ligand (CD137L) is expressed by …
family, is a potent T cell co-stimulatory molecule. CD137 ligand (CD137L) is expressed by …
Para‐inflammation‐mediated retinal recruitment of bone marrow‐derived myeloid cells following whole‐body irradiation is CCL2 dependent
Previous studies have shown that following whole‐body irradiation bone marrow (BM)‐
derived cells can migrate into the central nervous system, including the retina, to give rise to …
derived cells can migrate into the central nervous system, including the retina, to give rise to …
Chronic foot‐shock stress potentiates the influx of bone marrow‐derived microglia into hippocampus
M Brevet, H Kojima, A Asakawa… - Journal of …, 2010 - Wiley Online Library
For several years, a new population of microglia derived from bone marrow has been
described in multiple settings such as infection, trauma, and neurodegenerative disease …
described in multiple settings such as infection, trauma, and neurodegenerative disease …
Differential Detection and Distribution of Microglial and Hematogenous Macrophage Populations in the Injured Spinal Cord of lys-EGFP-ki Transgenic Mice
LA Mawhinney, SG Thawer, WY Lu… - … of Neuropathology & …, 2012 - academic.oup.com
The acute inflammatory response that follows spinal cord injury (SCI) contributes to
secondary injury that results in the expansion of the lesion and further loss of neurologic …
secondary injury that results in the expansion of the lesion and further loss of neurologic …
Physical insights into the blood–brain barrier translocation mechanisms
The number of individuals suffering from diseases of the central nervous system (CNS) is
growing with an aging population. While candidate drugs for many of these diseases are …
growing with an aging population. While candidate drugs for many of these diseases are …