Aims We aimed to determine the early changes and predictive value of left ventricular (LV)
segmental strain measures in women with breast cancer receiving doxorubicin. Methods …

Every year, more than a million people in the United States undergo chemotherapy or
radiation therapy for cancer, as estimated by the CDC. While chemotherapy has been an …

Background Doxorubicin has become the first-line antitumor drug clinically, but severely
limited by multiple side effects, especially cardiotoxicity. Liposomal doxorubicin therefore …

As in other cardiomyopathies, extracellular matrix (ECM) remodeling plays an important role
in anthracycline-induced cardiomyopathy. To understand the pattern and timing of ECM …

Similar to fullerenes, carbon nanotubes and graphene, carbon dots (CDs) are causing a lot
of research work in their own right. CDs are a type of surface-passivated quantum dot that …

Anthracyclines are among the most used chemotherapeutic agents in breast cancer (BC).
However their use is hampered by anthracycline-induced cardiotoxicity (AIC). The currently …

Mangiferin (MGF) is a natural and valuable polyphenol found in significant levels in many
plant species, including Cyclopia intermedia (C. intermedia). In a previous study, we …

A serious concern of doxorubicin (DOX) therapy is that it causes severe adverse effects,
particularly cardiotoxicity. Carbon monoxide (CO) possesses powerful cytoprotective effects …

Cardiovascular diseases (CVDs), the world's most prominent cause of mortality, continue to
be challenging conditions for patients, physicians, and researchers alike. CVDs comprise a …

Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor of infancy that is
commonly associated with a life-threatening thrombocytopenic condition, Kasabach-Merritt …