Preclinical evaluation of PEGylated liposomal doxorubicin as an effective radiosensitizer in chemoradiotherapy for lung cancer

JLY Chen, CK Pan, YL Lin, CY Tsai, YS Huang… - Strahlentherapie und …, 2021 - Springer
Purpose Development of a safe and effective systemic chemotherapeutic agent for
concurrent administration with definitive thoracic radiotherapy remains a major goal of lung …

Platelet functional abnormalities in pediatric patients with kaposiform hemangioendothelioma/Kasabach-Merritt phenomenon

AA Martyanov, IP Tesakov, LA Khachatryan… - Blood …, 2023 - ashpublications.org
Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor of infancy that is
commonly associated with a life-threatening thrombocytopenic condition, Kasabach-Merritt …

Co-Treatment of Caco-2 Cells with Doxorubicin and Gold Nanoparticles Produced from Cyclopia intermedia Extracts or Mangiferin Enhances Drug Effects

JA Aboyewa, NRS Sibuyi, M Goboza, LA Murtz… - Nanomaterials, 2022 - mdpi.com
Mangiferin (MGF) is a natural and valuable polyphenol found in significant levels in many
plant species, including Cyclopia intermedia (C. intermedia). In a previous study, we …

Dual immunotherapy alternating with anti-PD-1 antibody plus liposomal doxorubicin show good efficacy in prostate epithelioid hemangioendothelioma: a case report

J Zhang, Q Ye, X Yang, T Li, S Huang, P Zhou… - Frontiers in …, 2024 - frontiersin.org
Epithelioid hemangioendothelioma is a rare vascular malignancy, and currently, there is no
standard treatment regimen for this disease and existing treatment options have limited …

[HTML][HTML] Understanding the In Vitro-In Vivo Nexus: Advanced correlation models predict clinical performance of liposomal doxorubicin

K Gan, Z Li, PM Darli, T Wong, H Modh, P Gottier… - International Journal of …, 2024 - Elsevier
In the century of precision medicine and predictive modeling, addressing quality-related
issues in the medical supply chain is critical, with 62% of the disruptions being attributable to …

Recent advances in functional carbon quantum dots for antitumour

R Cai, L Xiao, M Liu, F Du, Z Wang - International Journal of …, 2021 - Taylor & Francis
Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional
photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their …

CT Images in Follicular Lymphoma: Changes after Treatment Are Predictive of Cardiac Toxicity in Patients Treated with Anthracycline-Based or RB Regimens

F Esposito, V Mezzanotte, C Tesei, A Luciano… - Cancers, 2024 - mdpi.com
Simple Summary Epicardial adipose tissue radio intensity and myocardial extracellular
volume in computed tomography were investigated and evaluated at disease onset and …

Isoquercitrin alleviates pirarubicin-induced cardiotoxicity in vivo and in vitro by inhibiting apoptosis through Phlpp1/AKT/Bcl-2 signaling pathway

L Wang, J Ma, C Chen, B Lin, S Xie, W Yang… - Frontiers in …, 2024 - frontiersin.org
Introduction: Due to the cardiotoxicity of pirarubicin (THP), it is necessary to investigate new
compounds for the treatment of THP-induced cardiotoxicity. Isoquercitrin (IQC) is a natural …

Hybrid polydimethylsiloxane (PDMS) incorporated thermogelling system for effective liver cancer treatment

P Ma, L Jiang, X Luo, J Chen, Q Wang, Y Chen, E Ye… - Pharmaceutics, 2022 - mdpi.com
For the delivery of anticancer drugs, an injectable in situ hydrogel with thermal
responsiveness and prolonged drug release capabilities shows considerable potential …

Anti-tumor therapy of glycyrrhetinic acid targeted liposome co-delivery of doxorubicin and berberine for hepatocellular carcinoma

N Xu, J Wu, W Wang, S Sun, M Sun, Y Bian… - Drug Delivery and …, 2024 - Springer
During the development of hepatocellular carcinoma (HCC), hepatic stellate cells undergo
activation and transform into cancer-associated fibroblasts (CAFs) due to the influence of …