Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Obesity remains the most important risk factor for the incidence and progression of
osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to …

Osteoarthritis (OA) is a family of degenerative diseases affecting multiple joint tissues.
Despite the diverse etiology and pathogenesis of OA, increasing evidence suggests that …

OBJECTIVE: Although osteoarthritis (OA) is considered a non-inflammatory condition, it is
widely accepted that synovial inflammation is a feature of OA. However, the role of immune …

Although osteoarthritis (OA) has been traditionally regarded as a non-inflammatory disease,
reports increasingly suggest that it is inflammatory, at least in certain patients. OA patients …

Concepts regarding osteoarthritis, the most common joint disease, have dramatically
changed in the past decade thanks to the development of new imaging techniques and the …

Objective. To get a better understanding of inflammatory pathways active in the osteoarthritic
(OA) joint, we characterized and compared inflammatory cells in the synovium and the …

Objective To define if adipose mesenchymal stromal cell (ASC) treatment mediated
switching of the pro-inflammatory profile of M1-like macrophages as a means to develop a …

Abstract Purpose of the Review Mounting evidence supports a role of low-grade
inflammation in the pathophysiology of osteoarthritis (OA). We review and discuss the role of …

Objective This study aimed to determine whether alignment correction by high tibial
osteotomy (HTO) can change the biologic intraarticular microenvironment of osteoarthritic …